Recent progress in the applications of gold-based nanoparticles towards tumor-targeted imaging and therapy

Cancer death rate remains high all over the world, scientists are paying increasing attention to meet the requirements for precise diagnosis and therapy. Therefore, early diagnosis and active treatment can effectively improve the five-year survival rate of patients. In recent years, gold-based nanom...

Full description

Saved in:
Bibliographic Details
Published in:RSC advances 2022-03, Vol.12 (13), p.7635-7651
Main Authors: Li, Xinxin, Zhang, Yiwei, Liu, GuangKuo, luo, Ziyi, Zhou, Lu, Xue, Yanan, Liu, Min
Format: Article
Language:English
Subjects:
Biocompatibility
Chemistry
Computed tomography
Diagnosis
Fluorescence
Gold
Medical imaging
Nanomaterials
Nanoparticles
Raman spectroscopy
Therapy
Toxicity
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Cancer death rate remains high all over the world, scientists are paying increasing attention to meet the requirements for precise diagnosis and therapy. Therefore, early diagnosis and active treatment can effectively improve the five-year survival rate of patients. In recent years, gold-based nanomaterials have received increasing attention in medical fields due to their excellent biocompatibility, low toxicity and unique properties. In addition, because of the inherent nature of gold nanomaterials including for computed tomography (CT), fluorescence/optical imaging (FI/OI), surface enhanced Raman spectroscopy imaging (SERS), photoacoustic imaging (PAI) and photothermal therapy (PTT), various gold nanomaterials were developed as theranostic nanoplatforms. In this review, we summarized the latest developments of nanomaterials in imaging and combined therapy, and the prospects for the future application of gold-based theranostic nanoplatforms were also proposed. We summarize the latest developments of gold nanomaterials in imaging and combined therapy as well as prospects for the future application of gold-based theranostic nanoplatforms.
ISSN:2046-2069
2046-2069
DOI:10.1039/d2ra00566b