The efficacy of tissue glue in pediatric circumcision wound approximation: A meta-analysis of randomized controlled trial

Tissue glue has been examined extensively for its effectiveness in pediatrics, and the findings are good. The purpose of this research was to examine the effectiveness of tissue glue compared to absorbable sutures for wound approximation in pediatric circumcision. A systematic review and meta-analys...

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Bibliographic Details
Published in:Journal of pediatric urology 2022-06, Vol.18 (3), p.327-333
Main Authors: Azmi, Yufi Aulia, Yogiswara, Niwanda, Renaldo, Johan
Format: Article
Language:English
Subjects:
Children
Circumcision
Complications
Efficacy
Tissue glue
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Summary:Tissue glue has been examined extensively for its effectiveness in pediatrics, and the findings are good. The purpose of this research was to examine the effectiveness of tissue glue compared to absorbable sutures for wound approximation in pediatric circumcision. A systematic review and meta-analysis on children who had circumcision using tissue glue and absorbable suture were done in line with the PRISMA criteria. RevMan 5.4 was used to perform the meta-analysis. The mean differences for continuous and dichotomous data are determined using inverse variance, and the odds ratio is calculated using the Mantel-Haenszel technique. The inclusion criteria were met by six trials containing a total of 817 patients. According to the analysis, tissue glue significantly reduces the duration of the operation (MD – 7.98; 95% CI -12.35, -3.62; p = 0.0003), pain severity (SMD -0.57; 95%CI -0.80, -0.32; p 
ISSN:1477-5131
1873-4898
DOI:10.1016/j.jpurol.2022.03.010