Autologous platelet-rich plasma 'fluid' versus 'gel' form in combination with fractional CO2 laser in the treatment of atrophic acne scars: a split-face randomized clinical trial

The treatment of atrophic acne scars represents a therapeutic challenge. Recently, plasma gel has been introduced among treatment modalities. To compare the efficacy of platelet-rich-plasma 'fluid' versus 'gel' form combined with fractional CO 2 laser in the treatment of atrophic...

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Bibliographic Details
Published in:The Journal of dermatological treatment 2022-07, Vol.33 (5), p.2654-2663
Main Authors: Gawdat, Heba I., El-Hadidy, Yasmin Ahmed, Allam, Riham S. H. M., Abdelkader, Heba Ahmed
Format: Article
Language:English
Subjects:
Acne scars
fractional CO
laser
plasma gel
platelet-rich plasma
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Summary:The treatment of atrophic acne scars represents a therapeutic challenge. Recently, plasma gel has been introduced among treatment modalities. To compare the efficacy of platelet-rich-plasma 'fluid' versus 'gel' form combined with fractional CO 2 laser in the treatment of atrophic acne scars. Twenty-seven patients with atrophic acne scars were included. Treatment with fractional CO 2 laser plus plasma fluid/gel was randomly assigned to the right/left sides of the face. Clinical and Optical Coherence Tomography (OCT) assessments were scheduled at baseline, one month, and three months after the last session. There was a significant improvement in clinical assessment scores at third-month follow-up on the plasma gel- and plasma fluid-treated sides compared to those at the first-month follow-up (p 
ISSN:0954-6634
1471-1753
DOI:10.1080/09546634.2022.2067816