The association between the prognostic nutritional index and 28-day mortality among atrial fibrillation patients in China over 80 years of age

• Published in: Nutrition, metabolism, and cardiovascular diseases metabolism, and cardiovascular diseases, 2022-06, Vol.32 (6), p.1493-1501
• Main Authors: Cai, Jiasheng, Chen, Conggai, Zhang, Lingyun, Zhai, Xinrong, Zhao, Xiaona, Ge, Jin, Chang, Xifeng, Song, Bin, Qu, Xinkai
• Format: Article
• Language: English
• Subjects: Atrial fibrillation; Cardiovascular disease; Mortality; Nutrition; Older
• ISSN: 0939-4753; 1590-3729
• DOI: 10.1016/j.numecd.2022.03.013

The most prevalent form of cardiac rhythm abnormality among older populations is atrial fibrillation (AF). The prognostic nutritional index (PNI) is a reliable predictor of mortality in various diseases. The association between the PNI and mortality among AF patients over 80 years remains uncleared. A retrospective assessment of AF cases admitted to a single cardiovascular disease unit in China between January 2015 and June 2020 was performed. The PNI at admission was defined as 10 × serum albumin (g/dL) + 0.005 × total lymphocyte count (per mm3). The association between PNI and cardiovascular disease (CVD)-related or all-cause mortality within 28 days was assessed via multivariable Cox regression. The analysis included 1141 patients. The CVD-related and all-cause mortality rates were 3.3% and 8.7%. Kaplan-Meier analyses revealed that cases with lower PNI tertiles exhibited higher all-cause mortality (T1: 7.6%; T2: 6.1%; T3: 2.4%, P