Hormonal Influence in Stress Urinary Incontinence During Pregnancy and Postpartum

Hormonal changes have been proposed as an etiological factor of stress urinary incontinence (SUI) during pregnancy. Our main objective was to demonstrate the role of hormones in SUI development during pregnancy and postpartum. A prospective longitudinal study was designed. Primiparous women without...

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Bibliographic Details
Published in:Reproductive sciences (Thousand Oaks, Calif.) Calif.), 2022-08, Vol.29 (8), p.2190-2199
Main Authors: Molinet Coll, Cristina, Martínez Franco, Eva, Altimira Queral, Laura, Cuadras, Daniel, Amat Tardiu, Lluís, Parés, David
Format: Article
Language:English
Subjects:
Embryology
General Gynecology: Original Article
Medicine
Medicine & Public Health
Obstetrics/Perinatology/Midwifery
Reproductive Medicine
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Summary:Hormonal changes have been proposed as an etiological factor of stress urinary incontinence (SUI) during pregnancy. Our main objective was to demonstrate the role of hormones in SUI development during pregnancy and postpartum. A prospective longitudinal study was designed. Primiparous women without previous urinary incontinence symptoms were included. Symptoms and Quality of Life (QoL) Questionnaires, physical examinations, and hormone concentration (progesterone, estradiol, and relaxin) were collected twice during pregnancy and three times during postpartum. Logistic regression models, with Wald’s forward variable selection method, were used. Prevalence of SUI was 11% in the first trimester, 50% in the third trimester, and 16.4% at 6 months postpartum. The risk of developing SUI throughout pregnancy is higher in women with higher progesterone concentration in the first trimester (OR 1.38, 95% CI 1.06–1.81, p  
ISSN:1933-7191
1933-7205
DOI:10.1007/s43032-022-00946-7