Targeted therapies for cardiac diseases

Heart failure is a systemic disease in which neuroendocrine activation, inflammation and metabolic changes can impair cardiac function. In addition, variants in genes encoding sarcomeric proteins can predispose individuals to develop heart failure. The 2022 Gordon Research Conference on Cardiac Regu...

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Bibliographic Details
Published in:Nature reviews cardiology 2022-06, Vol.19 (6), p.343-344
Main Authors: Maack, Christoph, Tardiff, Jil C.
Format: Article
Language:English
Subjects:
692/420
692/699/75/230
692/700/565
Antineoplastic Agents - therapeutic use
Cancer therapies
Cardiac function
Cardiac Imaging
Cardiac Surgery
Cardiology
Cardiomyopathy
Child development
Comment
Dehydrogenases
Disease
Ejection fraction
Heart attacks
Heart Diseases - drug therapy
Heart failure
Humans
Immune system
Inflammation
Medicine
Medicine & Public Health
Metabolic disorders
Molecular Targeted Therapy
Nervous system
Obesity
Physiology
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Summary:Heart failure is a systemic disease in which neuroendocrine activation, inflammation and metabolic changes can impair cardiac function. In addition, variants in genes encoding sarcomeric proteins can predispose individuals to develop heart failure. The 2022 Gordon Research Conference on Cardiac Regulatory Mechanisms aims to identify novel treatment targets by applying high-resolution approaches to complex cardiac disorders.
ISSN:1759-5002
1759-5010
1759-5010
DOI:10.1038/s41569-022-00704-x