Post-cholecystectomy bile reflux gastritis: Prevalence, risk factors, and clinical characteristics

Objective Bile reflux gastritis is caused by the backward flow of duodenal fluid into the stomach. A retrospective cohort study was performed to estimate the prevalence and risk factors of bile reflux gastritis postcholecystectomy, and to evaluate the endoscopic and histopathologic changes in gastri...

Full description

Saved in:
Bibliographic Details
Published in:Chronic illness 2023-09, Vol.19 (3), p.529-538
Main Authors: Othman, Amira AA, Dwedar, Amal AZ, ElSadek, Hany M, AbdElAziz, Hesham R, Abdelrahman, Abeer AF
Format: Article
Language:English
Subjects:
Abdominal pain
Bile
Cholecystectomy
Cohort analysis
Diabetes
Heartburn
Hospitals
Nausea
Obesity
Rib cage
Risk factors
Stomach
Vomiting
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective Bile reflux gastritis is caused by the backward flow of duodenal fluid into the stomach. A retrospective cohort study was performed to estimate the prevalence and risk factors of bile reflux gastritis postcholecystectomy, and to evaluate the endoscopic and histopathologic changes in gastric mucosa. Methods Patients with refractory upper abdominal pain right below the ribs with symptoms of bloating, burping, nausea, vomiting, and bile regurgitation during the period from January 2018 to December 2020, submitted to Zagazig University Hospitals were enrolled in this study. The studied 64 patients were divided into two groups; the control group (CG): 30 subjects who had never undergone any biliary interventions, and the post-cholecystectomy group (PCG): 34 patients who had undergone cholecystectomy. Results The prevalence of bile reflux gastritis was (16.7%) and (61.8%) in CG and PCG, respectively. Diabetes, obesity, elevated gastric bilirubin, and elevated stomach pH were all risk factors for bile reflux gastritis in both groups (r = .28,.48,.78,.57 respectively). Age, sex, epigastric pain, heartburn, vomiting, and the existence of bile reflux gastritis, on the other hand, had no correlation. Discussion After a cholecystectomy, bile reflux gastritis is prevalent, especially among obese and diabetic patients.
ISSN:1742-3953
1745-9206
DOI:10.1177/17423953221097440