Egyptian revalidation of non-invasive parameters for predicting esophageal varices in cirrhotic patients: A retrospective study

In resource-limited countries, non-invasive tests for assessing liver fibrosis are a potential alternative to costly endoscopic screening for esophageal varices. We aimed to validate several non-invasive parameters for predicting the presence of varices. Between September 2006 and August 2017, a tot...

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Bibliographic Details
Published in:Arab journal of gastroenterology 2022-05, Vol.23 (2), p.120-124
Main Authors: El-Kassas, Mohamed, Elakel, Wafaa, Alboraie, Mohamed, Ezzat, Reem, Abdelhakam, Sara, Hassany, Mohamed, Ali-Eldin, Zainab, Sherief, Ahmed F., Yosry, Ayman, El-Serafy, Magdy, El-Sayed, Manal Hamdy, Waked, Imam, Doss, Wahid, Esmat, Gamal
Format: Article
Language:English
Subjects:
Baveno guidelines
Cirrhosis
Esophageal varices
Non-invasive parameter
Portal hypertension
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Summary:In resource-limited countries, non-invasive tests for assessing liver fibrosis are a potential alternative to costly endoscopic screening for esophageal varices. We aimed to validate several non-invasive parameters for predicting the presence of varices. Between September 2006 and August 2017, a total of 46,014 patients who underwent upper gastrointestinal endoscopy as one of the perquisites for receiving hepatitis C virus (HCV) therapy were enrolled and divided into group I (without varices) and group II (with varices). Non-invasive parameters of fibrosis, namely Lok index, Bonacini score, liver stiffness, FIB-4, Baveno, and extended Baveno criteria, were validated. Lok index, Bonacini score, liver stiffness, and FIB-4 had areas under the receiver operating characteristic curve (AUCs) of >0.6 (all P 
ISSN:1687-1979
2090-2387
DOI:10.1016/j.ajg.2022.04.003