Evaluation of Atopic Dermatitis Improvement Caused by Low‐Level, Low‐Frequency Pulsed Electromagnetic Fields

This study aimed to evaluate the effectiveness of using low‐level, low‐frequency pulsed electromagnetic field (LLLF_PEMF) stimulation to improve atopic dermatitis induced by 2,4‐dinitrochlorobenzene (DNCB). Twenty 6‐week‐old hairless mice were randomly divided into Normal (n = 5), PEMF 15 Hz (n = 5)...

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Published in:Bioelectromagnetics 2022-05, Vol.43 (4), p.268-277
Main Authors: Kim, Jun‐Young, Lee, Ji‐Young, Lee, Ja‐Woo, Lee, Soo‐Kyung, Park, Chang‐Soon, Yang, Se‐Jung, Lee, Yong‐Heum
Format: Article
Language:English
Subjects:
1-Chloro-2,4-dinitrobenzene
Animals
Atopic dermatitis
Chemical reactions
Dermatitis
Dermatitis, Atopic - therapy
dinitrochlorobenzene
Eczema
Electromagnetic fields
Electromagnetic Fields - adverse effects
Hairless
hairless mouse
Immune response
inflammation
Lesions
Mice
pulsed electromagnetic field
Sensory evaluation
Stimulation
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container_title Bioelectromagnetics
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creator Kim, Jun‐Young
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Lee, Yong‐Heum
description This study aimed to evaluate the effectiveness of using low‐level, low‐frequency pulsed electromagnetic field (LLLF_PEMF) stimulation to improve atopic dermatitis induced by 2,4‐dinitrochlorobenzene (DNCB). Twenty 6‐week‐old hairless mice were randomly divided into Normal (n = 5), PEMF 15 Hz (n = 5), PEMF 75 Hz (n = 5), and Sham (n = 5) groups. Following the onset of atopic dermatitis symptoms, PEMF groups (15 and 75 Hz) were stimulated with LLLF_PEMF (15 mT) for 8 h per day for 1 week. Sensory evaluation analysis revealed a significant difference between the PEMF 15 Hz group and Sham group (P 
doi_str_mv 10.1002/bem.22405
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In conclusion, these results suggest that PEMF stimulation in vivo triggers electro‐chemical reactions that affect immune response. © 2022 Bioelectromagnetics Society.</description><identifier>ISSN: 0197-8462</identifier><identifier>EISSN: 1521-186X</identifier><identifier>DOI: 10.1002/bem.22405</identifier><identifier>PMID: 35476222</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>1-Chloro-2,4-dinitrobenzene ; Animals ; Atopic dermatitis ; Chemical reactions ; Dermatitis ; Dermatitis, Atopic - therapy ; dinitrochlorobenzene ; Eczema ; Electromagnetic fields ; Electromagnetic Fields - adverse effects ; Hairless ; hairless mouse ; Immune response ; inflammation ; Lesions ; Mice ; pulsed electromagnetic field ; Sensory evaluation ; Stimulation</subject><ispartof>Bioelectromagnetics, 2022-05, Vol.43 (4), p.268-277</ispartof><rights>2022 Society.</rights><rights>2022 Bioelectromagnetics Society.</rights><rights>2022 Bioelectromagnetics Society</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3535-8382f53622ececcfed140f7fc080615e7d3967a12329c2abdba9c0fc64f352733</citedby><cites>FETCH-LOGICAL-c3535-8382f53622ececcfed140f7fc080615e7d3967a12329c2abdba9c0fc64f352733</cites><orcidid>0000-0002-1241-525X ; 0000-0003-2195-6733</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35476222$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kim, Jun‐Young</creatorcontrib><creatorcontrib>Lee, Ji‐Young</creatorcontrib><creatorcontrib>Lee, Ja‐Woo</creatorcontrib><creatorcontrib>Lee, Soo‐Kyung</creatorcontrib><creatorcontrib>Park, Chang‐Soon</creatorcontrib><creatorcontrib>Yang, Se‐Jung</creatorcontrib><creatorcontrib>Lee, Yong‐Heum</creatorcontrib><title>Evaluation of Atopic Dermatitis Improvement Caused by Low‐Level, Low‐Frequency Pulsed Electromagnetic Fields</title><title>Bioelectromagnetics</title><addtitle>Bioelectromagnetics</addtitle><description>This study aimed to evaluate the effectiveness of using low‐level, low‐frequency pulsed electromagnetic field (LLLF_PEMF) stimulation to improve atopic dermatitis induced by 2,4‐dinitrochlorobenzene (DNCB). 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subjects 1-Chloro-2,4-dinitrobenzene
Animals
Atopic dermatitis
Chemical reactions
Dermatitis
Dermatitis, Atopic - therapy
dinitrochlorobenzene
Eczema
Electromagnetic fields
Electromagnetic Fields - adverse effects
Hairless
hairless mouse
Immune response
inflammation
Lesions
Mice
pulsed electromagnetic field
Sensory evaluation
Stimulation
title Evaluation of Atopic Dermatitis Improvement Caused by Low‐Level, Low‐Frequency Pulsed Electromagnetic Fields
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