PITing it forward: A new link in the journey of uropathogenic E. coli in the urothelium

Urinary tract infections (UTIs) are a cause for alarm given the high rates of treatment failure. In a recent issue of Cell Reports, Pang et al. uncovered dueling molecular machinery at the host-pathogen interface in response to phosphate that points to new anti-infective strategies against UTIs. Uri...

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Bibliographic Details
Published in:Cell reports (Cambridge) 2022-04, Vol.39 (4), p.110758-110758, Article 110758
Main Authors: Joshi, Chetanchandra S., Cegelski, Lynette, Mysorekar, Indira U.
Format: Article
Language:English
Subjects:
Escherichia coli Infections
Female
Humans
Male
Urinary Tract Infections
Uropathogenic Escherichia coli - physiology
Urothelium
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Summary:Urinary tract infections (UTIs) are a cause for alarm given the high rates of treatment failure. In a recent issue of Cell Reports, Pang et al. uncovered dueling molecular machinery at the host-pathogen interface in response to phosphate that points to new anti-infective strategies against UTIs. Urinary tract infections (UTIs) are a cause for alarm given the high rates of treatment failure. In a recent issue of Cell Reports, Pang et al. uncovered dueling molecular machinery at the host-pathogen interface in response to phosphate that points to new anti-infective strategies against UTIs.
ISSN:2211-1247
2211-1247
DOI:10.1016/j.celrep.2022.110758