SGLT inhibitors as antidiabetic agents: a comprehensive review

Diabetes is one of the most common disorders that substantially contributes to an increase in global health burden. As a metabolic disorder, diabetes is associated with various medical conditions and diseases such as obesity, hypertension, cardiovascular diseases, and atherosclerosis. In this review...

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Bibliographic Details
Published in:RSC advances 2020-01, Vol.1 (3), p.1733-1756
Main Authors: Kshirsagar, Rahul P, Kulkarni, Abhishek A, Chouthe, Rashmi S, Pathan, Shahebaaz K, Une, Hemant D, Reddy, G. Bhanuprakash, Diwan, Prakash V, Ansari, Siddique Akber, Sangshetti, Jaiprakash N
Format: Article
Language:English
Subjects:
Atherosclerosis
Chemistry
Diabetes
Hypertension
Inhibitors
Metabolic disorders
Organic chemistry
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Summary:Diabetes is one of the most common disorders that substantially contributes to an increase in global health burden. As a metabolic disorder, diabetes is associated with various medical conditions and diseases such as obesity, hypertension, cardiovascular diseases, and atherosclerosis. In this review, we cover the scientific studies on sodium/glucose cotransporter (SGLT) inhibitors published during the last decade. Our focus on providing an exhaustive overview of SGLT inhibitors enabled us to present their chemical classification for the first time. Diabetes is one of the most common disorders that substantially contributes to an increase in global health burden.
ISSN:2046-2069
2046-2069
DOI:10.1039/c9ra08706k