New types of silica-fortified magnetic nanoparticles as tools for molecular biology applications

The synthesis and physico-chemical characterization of superparamagnetic polysaccharide nanoparticles (200–400 nm) with an iron oxide content of 75–80% are described. The robustness of the particle matrix was increased by intercalation of nanoscaled silica. Electrokinetic and streaming potential mea...

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Bibliographic Details
Published in:Journal of magnetism and magnetic materials 1999, Vol.194 (1), p.8-15
Main Authors: Grüttner, Cordula, Teller, Joachim
Format: Article
Language:English
Subjects:
Biological and medical sciences
Charge density
Dextran
Diverse techniques
Fundamental and applied biological sciences. Psychology
Molecular and cellular biology
Nanoparticles
Silica
Zetapotential
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Summary:The synthesis and physico-chemical characterization of superparamagnetic polysaccharide nanoparticles (200–400 nm) with an iron oxide content of 75–80% are described. The robustness of the particle matrix was increased by intercalation of nanoscaled silica. Electrokinetic and streaming potential measurements have been carried out to optimize the silica content of the particles. Specific surface modifications for various in vitro particle applications can also be optimized using these measurements.
ISSN:0304-8853
DOI:10.1016/S0304-8853(98)00561-7