Rational design of yolk-shell nanostructures for drug delivery

Yolk-shell nanoparticles (YSNPs) are a new class of hollow nanostructures, and their unique properties can be utilized in drug delivery systems. The recent progress in YSNPs-based carriers is highlighted in drug delivery systems. Doxorubicin hydrochloride, ceftriaxone sodium, and methotrexate are th...

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Bibliographic Details
Published in:RSC advances 2020-08, Vol.1 (5), p.394-319
Main Authors: Mohammadi Ziarani, Ghodsi, Mofatehnia, Parisa, Mohajer, Fatemeh, Badiei, Alireza
Format: Article
Language:English
Subjects:
Chemical Sciences
Chemistry
Doxorubicin
Drug delivery systems
Methotrexate
Nanoparticles
Nanostructure
Toxicity
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Summary:Yolk-shell nanoparticles (YSNPs) are a new class of hollow nanostructures, and their unique properties can be utilized in drug delivery systems. The recent progress in YSNPs-based carriers is highlighted in drug delivery systems. Doxorubicin hydrochloride, ceftriaxone sodium, and methotrexate are three of the most common drugs that are used in this field. According to the reported studies, the materials used most often as yolk-shells are magnetic nanoparticles and polymers. The used methods for synthesizing a diverse array of YSNPs are classified based on their core structures. Various properties of YSNPs include their high drug-loading capacity, and their ability to decrease drug toxicity and satisfactorily and efficiently release drugs. The recent progress in yolk-shell nanoparticles (YSNPs) as a new class of hollow nanostructures applied for drug delivery.
ISSN:2046-2069
2046-2069
DOI:10.1039/d0ra03611k