Dietary fumonisin may compromise the nutritive value of feed and distort copper and zinc digestibility and retention in weaned piglets

• Published in: Journal of animal physiology and animal nutrition 2023-03, Vol.107 (2), p.504-517
• Main Authors: Zeebone, Y. Y., Kovács, M., Bóta, B., Zdeněk, V., Taubner, T., Halas, V.
• Format: Article
• Language: English
• Subjects: Animal Feed - analysis; Animal Nutritional Physiological Phenomena; Animals; Calcium; Copper; Copper - pharmacology; Diet; Dietary minerals; Dietary Supplements - analysis; Digestibility; Digestion; Digestive enzymes; Enzymes; Feeds; fumonisin; Fumonisins; Fumonisins - pharmacology; Heat shock proteins; Hsp70 protein; intestinal architecture; Intestine; Liver; Magnesium; Mineral metabolism; mineral retention; Minerals; Minerals - metabolism; Nitrogen; nutrients digestibility; Nutritive Value; Retention; Swine; weaned piglets; Zinc; Zinc - pharmacology
• ISSN: 0931-2439; 1439-0396
• DOI: 10.1111/jpn.13724

Fumonisins (FUM) have been reported to impede gut functioning in pigs. However, investigations into the possible effect on mineral metabolism are limited. Thus, the trial studied the apparent total tract digestibility (ATTD) and retention of dietary nitrogen and minerals, intestinal architecture, digestive enzymes activity and heat‐shock protein 70 (Hsp70) activity. Eighteen weaned piglets of 7 weeks old were assigned to three groups and their feed either contained 0, 15 or 30 mg FUM/kg for 21 days. ATTD and retention of dietary N and minerals were measured in a 5‐ day long balance trial between Day 17 and Day 21. The digestible and metabolisable energy (DE and ME) content of the feeds were also determined. The body weights, cumulative feed intake, relative organ weights, digestive enzymes activity and intestinal morphology were not affected (p > 0.05) by dietary treatments. The DE content was significantly lower (p  0.05) by treatments. The ATTD and relative retention of Cu and Zn were remarkably (p