Homing in on cognition with cross-sectional analysis of sarcopenia-related measurements: the SARCOG study

• Published in: Aging clinical and experimental research 2022-05, Vol.34 (9), p.2149-2154
• Main Authors: Kara, Özgür, Kara, Murat, Kaymak, Bayram, Kaya, Tuğçe Cansu, Çıtır, Beyza Nur, Durmuş, Mahmut Esad, Durmuşoğlu, Esra, Doğan, Yahya, Tiftik, Tülay, Turan, Gökhan, Gürçay, Eda, Analay, Pelin, Ocak, Hasan, Şener, Fatıma Edibe, Özçakar, Levent
• Format: Article
• Language: English
• Subjects: Cognition & reasoning; Cognitive ability; Cross-sectional studies; Gait; Geriatrics/Gerontology; Medicine; Medicine & Public Health; Muscle function; Original Article; Sarcopenia
• ISSN: 1720-8319; 1594-0667; 1720-8319
• DOI: 10.1007/s40520-022-02145-5

Background Cognitive impairment may cause significant decline in muscle function and physical performance via affecting the neuromotor control. Aim To investigate the relationship between cognition and sarcopenia-related parameters in middle-aged and older adults. Methods Demographic data and comorbidities of adults ≥ 45-year-old were noted. The Mini-Mental State Examination (MMSE) was used to evaluate global cognitive function. Sonographic anterior midthigh muscle thickness, handgrip strength, chair stand test (CST) and gait speed were measured. The diagnosis of sarcopenia was established if low muscle mass was combined with low muscle function. Dynapenia was defined as low grip strength or increased CST duration. Results Among 1542 subjects (477 M, 1065 F), sarcopenia and dynapenia were detected in 22.6 and 17.2% of males, and 17.2 and 25.3% of females, respectively. Sarcopenic patients were older and had higher body mass index, higher frequencies of hypertension, diabetes mellitus and obesity. They had lower muscle thickness, grip strength in males only, CST performance in females only and gait speed than the other groups (all p