Relationship between different hepatitis B virus infection status and gestational diabetes mellitus prevalence among pregnant women with chronic HBV infection: A retrospective study

To investigate the relationships between different hepatitis B virus (HBV) infection status and gestational diabetes mellitus (GDM) and analyse the potential risk factors, we conducted an observational retrospective study in HBV‐infected pregnant women to compare the differences of GDM prevalence an...

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Bibliographic Details
Published in:Journal of viral hepatitis 2022-08, Vol.29 (8), p.596-603
Main Authors: Zhou, Guanlun, Chen, Chao, Han, Guorong, Jiang, Hongxiu, Cao, Minkai
Format: Article
Language:English
Subjects:
Chronic infection
Deoxyribonucleic acid
Diabetes mellitus
DNA
Gestational diabetes
gestational diabetes mellitus
Hepatitis B
Hepatitis B e antigen
hepatitis B e antigens
Hepatitis B surface antigen
hepatitis B virus
Infections
Liver
liver function
Pregnancy
Risk factors
viral load
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Summary:To investigate the relationships between different hepatitis B virus (HBV) infection status and gestational diabetes mellitus (GDM) and analyse the potential risk factors, we conducted an observational retrospective study in HBV‐infected pregnant women to compare the differences of GDM prevalence and clinical outcomes between groups divided by HBV infection status. Spearman's correlation coefficient was used to evaluate the correlations among hepatitis B e antigen (HBeAg), HBV DNA and liver function. Logistic regression model was used to analyse the risk factors. In all, 1390 HBsAg‐positive pregnant women were enrolled. HBeAg titre and HBV DNA, ALT and AST were correlated (r = 0.743, p 
ISSN:1352-0504
1365-2893
DOI:10.1111/jvh.13700