Micro-/nano-fluidic devices and in vivo fluorescence imaging based on quantum dots for cytologic diagnosis

Semiconductor quantum dots (QDs) possess attractive merits over traditional organic dyes, such as tunable emission, narrow emission spectra and good resistance against optical bleaching, and play a vital role in biosensing and bioimaging for cytologic diagnoses. Microfluidic technology is a potentia...

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Bibliographic Details
Published in:Lab on a chip 2022-06, Vol.22 (12), p.2223-2236
Main Authors: Luo, Minchuan, Yukawa, Hiroshi, Baba, Yoshinobu
Format: Article
Language:English
Subjects:
Biological activity
Bleaching
Emission spectra
Fluorescence
Medical imaging
Microfluidics
Quantum dots
Stem cells
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Summary:Semiconductor quantum dots (QDs) possess attractive merits over traditional organic dyes, such as tunable emission, narrow emission spectra and good resistance against optical bleaching, and play a vital role in biosensing and bioimaging for cytologic diagnoses. Microfluidic technology is a potentially useful strategy, as it provides a rapid platform for tracing of disease markers. fluorescence imaging (FI) based on QDs has become popular for the analysis of complex biological processes. We herein report the applications of multifunctional fluorescent QDs as sensitive probes for diagnoses on cancer medicine and stem cell therapy microfluidic chips and imaging.
ISSN:1473-0197
1473-0189
DOI:10.1039/d2lc00113f