Modification of reconstruction of left ventricular outflow tract, aortic root and the intervalvular fibrous body for extensive infective endocarditis: a single-centre experience

• Published in: European journal of cardio-thoracic surgery 2022-07, Vol.62 (2)
• Main Authors: El-Sayed Ahmad, Ali, Salamate, Saad, Amer, Mohamed, Abdullaahi, Abdisalan, Bayram, Ali, Sirat, Sami, Bakhtiary, Farhad
• Format: Article
• Language: English
• ISSN: 1873-734X; 1873-734X
• DOI: 10.1093/ejcts/ezac311

Abstract OBJECTIVES Extensive infective endocarditis (IE) stays a serious life-threatening disease with high mortality and morbidity. The aim of this study is to analyse our experience with our modified surgical technique for extensive IE during the last 4 years. METHODS Between March 2017 and February 2021, all patients with extensive IE required our modified technique consisting of a radical surgical resection of all infected cardiac tissues, the replacement of infected valves and a reconstruction of the intervalvular fibrous body, the aortic root and the left ventricular outflow tract with modified elephant trunk were included in this study. RESULTS Our modified technique was performed on 41 patients during the study period. The age median was 74 [interquartile range (IQR): 66.5–76.5] and 61.0% (n = 25) were female. Thirty-three patients (80.5%) were in New York Heart Association Class III–IV and 7 patients (17.1%) in cardiogenic shock. The median logistic European system for cardiac operative risk evaluation II as predicted risk of mortality was 35% (IQR: 28–78%). The median cardiopulmonary bypass time and cross-clamping time were 126 (IQR: 86.5–191) and 78 (IQR: 55.5–108) min, respectively. Intraoperative mortality and 30-day mortality were 4.8% (2 patients) and 19.5% (8 patients), respectively. Low cardiac output with necessity for mechanical support, stroke and new renal dialysis developed in 9.8% (4 patients), 17.1% (7 patients) and 22.0% (9 patients), respectively. New pacemaker implantation was noted in 39.0% (16 patients). Intensive care stay and hospital stay had medians of 6 (IQR: 5–12) and 14 (IQR: 12.5–20.5) days, respectively. One-year mortality and 4-year mortality were 34.1% (14 patients) and 39.0% (16 patients), respectively. Kaplan–Meier survival estimates were 60.3% (95% confidence interval: 46.2–78.6%) at 3 years. CONCLUSIONS Our modified technique can be performed in patients with extensive IE with acceptable early and mid-term morbidity and mortality. We believe that this technique is an available option for this ill-fated group of patients. Infective endocarditis (IE) is a life-threatening condition affecting 3–15 patients per 100,000 with a high morbidity and mortality [1–3].