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A methodology for obtaining and using toxic potency data for fire hazard analysis
A comprehensive methodology has been developed for obtaining and using smoke toxicity data for fire hazard analysis. This description of the methodology comprises (1) determination that the post-flashover fire is the proper focus of smoke inhalation deaths; criteria for a useful bench-scale toxic po...
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Published in: | Fire safety journal 1998-11, Vol.31 (4), p.345-358 |
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Main Authors: | , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that cite this one |
Online Access: | Get full text |
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Summary: | A comprehensive methodology has been developed for obtaining and using smoke toxicity data for fire hazard analysis. This description of the methodology comprises (1) determination that the post-flashover fire is the proper focus of smoke inhalation deaths; criteria for a useful bench-scale toxic potency (
LC
50) measurement method; (2) a method which meets these criteria, especially validation against real-scale fires; (3) a computational procedure for correcting the results from the bench-scale test for the CO levels observed in real-scale post-flashover fires; (4) procedures for reducing the usage of animals and broadening the applicability of data by interpreting gas measurement data using the N-Gas Model; and (5) a procedure for identifying whether a product produces smoke within the ordinary range of toxic potency for postflashover fires. |
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ISSN: | 0379-7112 |
DOI: | 10.1016/S0379-7112(98)00013-7 |