Increased Morbidity and Mortality After Hepatectomy for Colorectal Liver Metastases in Frail Patients is Largely Driven by Worse Outcomes After Minor Hepatectomy: It’s Not “Just a Wedge”

Background Frailty is associated with postoperative mortality, but its significance after hepatectomy for colorectal liver metastases (CRLM) is poorly defined. This study evaluated the impact of frailty after hepatectomy for CRLM. Methods The study identified 8477 patients in National Surgical Quali...

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Bibliographic Details
Published in:Annals of surgical oncology 2022-09, Vol.29 (9), p.5476-5485
Main Authors: Leigh, Natasha, Williams, Gregory A., Strasberg, Steven M., Fields, Ryan C., Hawkins, William G., Hammill, Chet W., Sanford, Dominic E.
Format: Article
Language:English
Subjects:
Frailty
Hepatectomy
Hepatobiliary Tumors
Liver
Medicine
Medicine & Public Health
Metastases
Metastasis
Morbidity
Mortality
Multivariate analysis
Oncology
Patients
Quality control
Regression analysis
Surgery
Surgical Oncology
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Summary:Background Frailty is associated with postoperative mortality, but its significance after hepatectomy for colorectal liver metastases (CRLM) is poorly defined. This study evaluated the impact of frailty after hepatectomy for CRLM. Methods The study identified 8477 patients in National Surgical Quality Improvement Program databases from 2014 to 2019 and stratified them by frailty score using the risk analysis index as very frail (>90th percentile), frail (75th–90th percentile), or non-frail (
ISSN:1068-9265
1534-4681
DOI:10.1245/s10434-022-11830-8