Sensitive and Rapid Diagnosis of Respiratory Virus Coinfection Using a Microfluidic Chip‐Powered CRISPR/Cas12a System

The ongoing pandemic caused by severe acute respiratory syndrome coronavirus 2 is profoundly influencing the global healthcare system and people's daily lives. The high resource consumption of coronavirus disease 2019 (COVID‐19) is resulting in insufficient surveillance of coinfection or resurg...

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Bibliographic Details
Published in:Small (Weinheim an der Bergstrasse, Germany) Germany), 2022-07, Vol.18 (26), p.e2200854-n/a
Main Authors: Liu, Jiajia, Wang, Huili, Zhang, Li, Lu, Ying, Wang, Xu, Shen, Minjie, Li, Nan, Feng, Li, Jing, Juhui, Cao, Bin, Zou, Xiaohui, Cheng, Jing, Xu, Youchun
Format: Article
Language:English
Subjects:
Amplification
Coronaviruses
COVID-19
CRISPR
Diagnosis
Microfluidics
multiplex diagnosis
Nanotechnology
point‐of‐care testing
respiratory disease
Respiratory diseases
Severe acute respiratory syndrome
Severe acute respiratory syndrome coronavirus 2
Surveillance
Viral diseases
Viruses
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Summary:The ongoing pandemic caused by severe acute respiratory syndrome coronavirus 2 is profoundly influencing the global healthcare system and people's daily lives. The high resource consumption of coronavirus disease 2019 (COVID‐19) is resulting in insufficient surveillance of coinfection or resurgence of other critical respiratory epidemics, which is of public concern. To facilitate evaluation of the current coinfection situation, a microfluidic system (MAPnavi) is developed for the rapid (
ISSN:1613-6810
1613-6829
DOI:10.1002/smll.202200854