Comparison of noninvasive follow-up testing in patients after percutaneous coronary intervention with drug-eluting stent implantation

• Published in: Journal of cardiology 2022-09, Vol.80 (3), p.275-282
• Main Authors: Seki, Tomotsugu, Takeuchi, Masato, Kawakami, Koji
• Format: Article
• Language: English
• Subjects: Coronary angiography; Coronary artery disease; Coronary computed tomography angiography; Noninvasive stress testing; Percutaneous coronary intervention
• ISSN: 0914-5087; 1876-4738
• DOI: 10.1016/j.jjcc.2022.05.001

This study sought to elucidate the trend of noninvasive follow-up testing in Japan and its impact on subsequent resource use and clinical outcomes after drug-eluting stent (DES) implantation. This retrospective study used data from a Japanese nationwide administrative database. We performed trend analyses for patients who underwent DES implantation from 2013 to 2019 and further analyzed who received at least one noninvasive follow-up testing. We compared stress electrocardiography (ECG), coronary computed tomography angiography (CCTA), and myocardial perfusion imaging (MPI) and outcomes using inverse probability weighting with generalized propensity scores. Primary outcomes included subsequent coronary angiography (CAG) and re-percutaneous coronary intervention (re-PCI). In trend analysis, 23.7% of patients underwent noninvasive follow-up testing, and 47.5% underwent CAG without preceding noninvasive follow-up testing. Total follow-up tests and CAG declined, whereas stress ECG, CCTA, and MPI increased (p for trend