Total laryngectomy negatively impacts sinonasal and olfactory-specific quality of life

The purpose of this study is to characterize deficits in olfactory-specific and sinonasal-specific QoL after total laryngectomy (TL) with validated patient reported outcome measures. Thirty patients who had a TL were prospectively enrolled. Patient demographics, as well as scores from the Questionna...

Full description

Saved in:
Bibliographic Details
Published in:American journal of otolaryngology 2022-07, Vol.43 (4), p.103471-103471, Article 103471
Main Authors: Chen, Joy, Solis, Roberto N., Mehrzad, Mehrnaz, Gill, Amarbir, Garber, Beverly, Beliveau, Angela M., Bewley, Arnaud F., Steele, Toby O., Birkeland, Andrew C., Abouyared, Marianne
Format: Article
Language:English
Subjects:
Head & neck cancer
Head and neck cancer
Likert scale
Olfaction
Olfaction disorders
Patients
QOD-NS
Quality of life
Questionnaires
SNOT-22
Surgery
Total laryngectomy
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c436t-505e0c205bdf4e97a03052909f4faf57a256df413b3e3f448a9d11e85921cf633
cites cdi_FETCH-LOGICAL-c436t-505e0c205bdf4e97a03052909f4faf57a256df413b3e3f448a9d11e85921cf633
container_end_page 103471
container_issue 4
container_start_page 103471
container_title American journal of otolaryngology
container_volume 43
creator Chen, Joy
Solis, Roberto N.
Mehrzad, Mehrnaz
Gill, Amarbir
Garber, Beverly
Beliveau, Angela M.
Bewley, Arnaud F.
Steele, Toby O.
Birkeland, Andrew C.
Abouyared, Marianne
description The purpose of this study is to characterize deficits in olfactory-specific and sinonasal-specific QoL after total laryngectomy (TL) with validated patient reported outcome measures. Thirty patients who had a TL were prospectively enrolled. Patient demographics, as well as scores from the Questionnaire of Olfactory Disorders Negative Statements (QOD-NS) and the Sino-nasal Outcome Test-22 (SNOT-22) were collected. Univariate analysis was performed to assess associations between patient characteristics and QoL scores. The average QOD-NS score was 37.9 ± 11.4 (20 indicates a moderate/severe impact on QoL). The abnormal QOD-NS group had a greater percentage of former smokers compared to the normal group (77.8% vs. 58.1%; P = 0.56) and more median days from surgery compared to the normal group (904 vs. 477 days; P = 0.24). Olfactory dysfunction associated with TL results in blunting of olfactory-specific QoL.
doi_str_mv 10.1016/j.amjoto.2022.103471
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2671999333</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0196070922000989</els_id><sourcerecordid>2671999333</sourcerecordid><originalsourceid>FETCH-LOGICAL-c436t-505e0c205bdf4e97a03052909f4faf57a256df413b3e3f448a9d11e85921cf633</originalsourceid><addsrcrecordid>eNp9kE1r3DAQhkVpaLbb_oNSDL3k4s1IsmzrUgghbQOBXJKQm9DKoyAjWxvJDvjfR4vTHnLoaeCdZz54CPlGYUeB1uf9Tg99mMKOAWM54lVDP5ANFZyVLW0fP5INUFmX0IA8JZ9T6gEyxMUncspFzWtoqw15uAuT9oXXcRmf0ExhWIoRn_TkXtAvhRsO2kypSG4Mo06Z1GNXBG9zGuJSpgMaZ50pnmft3bQUwRbeWfxCTqz2Cb--1S25_3V1d_mnvLn9fX15cVOaitdTKUAgGAZi39kKZaOBg2ASpK2stqLRTNS5Q_meI7dV1WrZUYqtkIwaW3O-JWfr3kMMzzOmSQ0uGfRejxjmpFjdUCkl50f0xzu0D3Mc83dHSjCQIlvZkmqlTAwpRbTqEN2Q7SgK6uhd9Wr1ro7e1eo9j31_Wz7vB-z-Df0VnYGfK4DZxovDqJJxOBrsXMzaVRfc_y-8AodulbU</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2675209556</pqid></control><display><type>article</type><title>Total laryngectomy negatively impacts sinonasal and olfactory-specific quality of life</title><source>ScienceDirect Journals</source><creator>Chen, Joy ; Solis, Roberto N. ; Mehrzad, Mehrnaz ; Gill, Amarbir ; Garber, Beverly ; Beliveau, Angela M. ; Bewley, Arnaud F. ; Steele, Toby O. ; Birkeland, Andrew C. ; Abouyared, Marianne</creator><creatorcontrib>Chen, Joy ; Solis, Roberto N. ; Mehrzad, Mehrnaz ; Gill, Amarbir ; Garber, Beverly ; Beliveau, Angela M. ; Bewley, Arnaud F. ; Steele, Toby O. ; Birkeland, Andrew C. ; Abouyared, Marianne</creatorcontrib><description>The purpose of this study is to characterize deficits in olfactory-specific and sinonasal-specific QoL after total laryngectomy (TL) with validated patient reported outcome measures. Thirty patients who had a TL were prospectively enrolled. Patient demographics, as well as scores from the Questionnaire of Olfactory Disorders Negative Statements (QOD-NS) and the Sino-nasal Outcome Test-22 (SNOT-22) were collected. Univariate analysis was performed to assess associations between patient characteristics and QoL scores. The average QOD-NS score was 37.9 ± 11.4 (&lt;38.5 is considered abnormal) and average SNOT-22 score was 32.0 ± 3.8 (&gt;20 indicates a moderate/severe impact on QoL). The abnormal QOD-NS group had a greater percentage of former smokers compared to the normal group (77.8% vs. 58.1%; P = 0.56) and more median days from surgery compared to the normal group (904 vs. 477 days; P = 0.24). Olfactory dysfunction associated with TL results in blunting of olfactory-specific QoL.</description><identifier>ISSN: 0196-0709</identifier><identifier>EISSN: 1532-818X</identifier><identifier>DOI: 10.1016/j.amjoto.2022.103471</identifier><identifier>PMID: 35636084</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Head &amp; neck cancer ; Head and neck cancer ; Likert scale ; Olfaction ; Olfaction disorders ; Patients ; QOD-NS ; Quality of life ; Questionnaires ; SNOT-22 ; Surgery ; Total laryngectomy</subject><ispartof>American journal of otolaryngology, 2022-07, Vol.43 (4), p.103471-103471, Article 103471</ispartof><rights>2022 The Authors</rights><rights>Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved.</rights><rights>2022. The Authors</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c436t-505e0c205bdf4e97a03052909f4faf57a256df413b3e3f448a9d11e85921cf633</citedby><cites>FETCH-LOGICAL-c436t-505e0c205bdf4e97a03052909f4faf57a256df413b3e3f448a9d11e85921cf633</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35636084$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chen, Joy</creatorcontrib><creatorcontrib>Solis, Roberto N.</creatorcontrib><creatorcontrib>Mehrzad, Mehrnaz</creatorcontrib><creatorcontrib>Gill, Amarbir</creatorcontrib><creatorcontrib>Garber, Beverly</creatorcontrib><creatorcontrib>Beliveau, Angela M.</creatorcontrib><creatorcontrib>Bewley, Arnaud F.</creatorcontrib><creatorcontrib>Steele, Toby O.</creatorcontrib><creatorcontrib>Birkeland, Andrew C.</creatorcontrib><creatorcontrib>Abouyared, Marianne</creatorcontrib><title>Total laryngectomy negatively impacts sinonasal and olfactory-specific quality of life</title><title>American journal of otolaryngology</title><addtitle>Am J Otolaryngol</addtitle><description>The purpose of this study is to characterize deficits in olfactory-specific and sinonasal-specific QoL after total laryngectomy (TL) with validated patient reported outcome measures. Thirty patients who had a TL were prospectively enrolled. Patient demographics, as well as scores from the Questionnaire of Olfactory Disorders Negative Statements (QOD-NS) and the Sino-nasal Outcome Test-22 (SNOT-22) were collected. Univariate analysis was performed to assess associations between patient characteristics and QoL scores. The average QOD-NS score was 37.9 ± 11.4 (&lt;38.5 is considered abnormal) and average SNOT-22 score was 32.0 ± 3.8 (&gt;20 indicates a moderate/severe impact on QoL). The abnormal QOD-NS group had a greater percentage of former smokers compared to the normal group (77.8% vs. 58.1%; P = 0.56) and more median days from surgery compared to the normal group (904 vs. 477 days; P = 0.24). Olfactory dysfunction associated with TL results in blunting of olfactory-specific QoL.</description><subject>Head &amp; neck cancer</subject><subject>Head and neck cancer</subject><subject>Likert scale</subject><subject>Olfaction</subject><subject>Olfaction disorders</subject><subject>Patients</subject><subject>QOD-NS</subject><subject>Quality of life</subject><subject>Questionnaires</subject><subject>SNOT-22</subject><subject>Surgery</subject><subject>Total laryngectomy</subject><issn>0196-0709</issn><issn>1532-818X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNp9kE1r3DAQhkVpaLbb_oNSDL3k4s1IsmzrUgghbQOBXJKQm9DKoyAjWxvJDvjfR4vTHnLoaeCdZz54CPlGYUeB1uf9Tg99mMKOAWM54lVDP5ANFZyVLW0fP5INUFmX0IA8JZ9T6gEyxMUncspFzWtoqw15uAuT9oXXcRmf0ExhWIoRn_TkXtAvhRsO2kypSG4Mo06Z1GNXBG9zGuJSpgMaZ50pnmft3bQUwRbeWfxCTqz2Cb--1S25_3V1d_mnvLn9fX15cVOaitdTKUAgGAZi39kKZaOBg2ASpK2stqLRTNS5Q_meI7dV1WrZUYqtkIwaW3O-JWfr3kMMzzOmSQ0uGfRejxjmpFjdUCkl50f0xzu0D3Mc83dHSjCQIlvZkmqlTAwpRbTqEN2Q7SgK6uhd9Wr1ro7e1eo9j31_Wz7vB-z-Df0VnYGfK4DZxovDqJJxOBrsXMzaVRfc_y-8AodulbU</recordid><startdate>20220701</startdate><enddate>20220701</enddate><creator>Chen, Joy</creator><creator>Solis, Roberto N.</creator><creator>Mehrzad, Mehrnaz</creator><creator>Gill, Amarbir</creator><creator>Garber, Beverly</creator><creator>Beliveau, Angela M.</creator><creator>Bewley, Arnaud F.</creator><creator>Steele, Toby O.</creator><creator>Birkeland, Andrew C.</creator><creator>Abouyared, Marianne</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>6I.</scope><scope>AAFTH</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7QR</scope><scope>7TK</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20220701</creationdate><title>Total laryngectomy negatively impacts sinonasal and olfactory-specific quality of life</title><author>Chen, Joy ; Solis, Roberto N. ; Mehrzad, Mehrnaz ; Gill, Amarbir ; Garber, Beverly ; Beliveau, Angela M. ; Bewley, Arnaud F. ; Steele, Toby O. ; Birkeland, Andrew C. ; Abouyared, Marianne</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c436t-505e0c205bdf4e97a03052909f4faf57a256df413b3e3f448a9d11e85921cf633</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Head &amp; neck cancer</topic><topic>Head and neck cancer</topic><topic>Likert scale</topic><topic>Olfaction</topic><topic>Olfaction disorders</topic><topic>Patients</topic><topic>QOD-NS</topic><topic>Quality of life</topic><topic>Questionnaires</topic><topic>SNOT-22</topic><topic>Surgery</topic><topic>Total laryngectomy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chen, Joy</creatorcontrib><creatorcontrib>Solis, Roberto N.</creatorcontrib><creatorcontrib>Mehrzad, Mehrnaz</creatorcontrib><creatorcontrib>Gill, Amarbir</creatorcontrib><creatorcontrib>Garber, Beverly</creatorcontrib><creatorcontrib>Beliveau, Angela M.</creatorcontrib><creatorcontrib>Bewley, Arnaud F.</creatorcontrib><creatorcontrib>Steele, Toby O.</creatorcontrib><creatorcontrib>Birkeland, Andrew C.</creatorcontrib><creatorcontrib>Abouyared, Marianne</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of otolaryngology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chen, Joy</au><au>Solis, Roberto N.</au><au>Mehrzad, Mehrnaz</au><au>Gill, Amarbir</au><au>Garber, Beverly</au><au>Beliveau, Angela M.</au><au>Bewley, Arnaud F.</au><au>Steele, Toby O.</au><au>Birkeland, Andrew C.</au><au>Abouyared, Marianne</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Total laryngectomy negatively impacts sinonasal and olfactory-specific quality of life</atitle><jtitle>American journal of otolaryngology</jtitle><addtitle>Am J Otolaryngol</addtitle><date>2022-07-01</date><risdate>2022</risdate><volume>43</volume><issue>4</issue><spage>103471</spage><epage>103471</epage><pages>103471-103471</pages><artnum>103471</artnum><issn>0196-0709</issn><eissn>1532-818X</eissn><abstract>The purpose of this study is to characterize deficits in olfactory-specific and sinonasal-specific QoL after total laryngectomy (TL) with validated patient reported outcome measures. Thirty patients who had a TL were prospectively enrolled. Patient demographics, as well as scores from the Questionnaire of Olfactory Disorders Negative Statements (QOD-NS) and the Sino-nasal Outcome Test-22 (SNOT-22) were collected. Univariate analysis was performed to assess associations between patient characteristics and QoL scores. The average QOD-NS score was 37.9 ± 11.4 (&lt;38.5 is considered abnormal) and average SNOT-22 score was 32.0 ± 3.8 (&gt;20 indicates a moderate/severe impact on QoL). The abnormal QOD-NS group had a greater percentage of former smokers compared to the normal group (77.8% vs. 58.1%; P = 0.56) and more median days from surgery compared to the normal group (904 vs. 477 days; P = 0.24). Olfactory dysfunction associated with TL results in blunting of olfactory-specific QoL.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>35636084</pmid><doi>10.1016/j.amjoto.2022.103471</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0196-0709
ispartof American journal of otolaryngology, 2022-07, Vol.43 (4), p.103471-103471, Article 103471
issn 0196-0709
1532-818X
language eng
recordid cdi_proquest_miscellaneous_2671999333
source ScienceDirect Journals
subjects Head & neck cancer
Head and neck cancer
Likert scale
Olfaction
Olfaction disorders
Patients
QOD-NS
Quality of life
Questionnaires
SNOT-22
Surgery
Total laryngectomy
title Total laryngectomy negatively impacts sinonasal and olfactory-specific quality of life
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-02T03%3A05%3A02IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Total%20laryngectomy%20negatively%20impacts%20sinonasal%20and%20olfactory-specific%20quality%20of%20life&rft.jtitle=American%20journal%20of%20otolaryngology&rft.au=Chen,%20Joy&rft.date=2022-07-01&rft.volume=43&rft.issue=4&rft.spage=103471&rft.epage=103471&rft.pages=103471-103471&rft.artnum=103471&rft.issn=0196-0709&rft.eissn=1532-818X&rft_id=info:doi/10.1016/j.amjoto.2022.103471&rft_dat=%3Cproquest_cross%3E2671999333%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c436t-505e0c205bdf4e97a03052909f4faf57a256df413b3e3f448a9d11e85921cf633%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2675209556&rft_id=info:pmid/35636084&rfr_iscdi=true