Changes in asphericity of anterior and posterior corneal surfaces for mild–moderate and high myopia after topography-guided FS-LASIK

• Published in: International ophthalmology 2022-11, Vol.42 (11), p.3555-3565
• Main Authors: Wu, Yuan, Sun, Shengshu, Liu, Zhanglin, Wang, Shuhan, Wang, Guiqin, Zhao, Shaozhen, Wei, Ruihua, Huang, Yue
• Format: Article
• Language: English
• Subjects: Asphericity; Cornea; Medicine; Medicine & Public Health; Myopia; Ophthalmology; Original Paper; Patients; Q values; Surgery; Topography
• ISSN: 1573-2630; 0165-5701; 1573-2630
• DOI: 10.1007/s10792-022-02356-9

Purpose To compare changes in asphericity of anterior and posterior corneal surfaces for different myopia patients after corneal topography-guided femtosecond-assisted laser in situ keratomileuses (FS-LASIK), and to analyze correlations between asphericity of corneal surfaces and preoperative spherical equivalence (SEQ). Methods In this prospective study, 59 patients who underwent corneal topography-guided FS-LASIK surgery were enrolled and divided into the mild–moderate myopia group (67 eyes) and the high myopia group (44 eyes). Postoperative follow-ups were performed at 1, 3, and 6 months. Postoperative changes in aspherical coefficient ( Q values), corneal higher-order aberrations (HOAs), and spherical aberrations (Z 4 0 ) were compared between the two groups. Relevance between Q value changes and SEQ, HOAs, and Z 4 0 as well as between SEQ and changes of HOAs and Z 4 0 was analyzed. Results There was a significant increase in Q values of the anterior (each diameter) and posterior (6–8 mm) corneal surface in both groups than before surgery ( P