Meningeal Rosai-Dorfman Disease Presenting as an Intracranial Mass – Report of a Case with Review of the Literature

Meningeal Rosai-Dorfman disease, a type of sporadic Rosai-Dorfman disease, is a rare occurrence. A few cases are reported in the English literature with an adequate immunohistochemical workup. This entity clinically and radiologically mimics either a meningeal or a parenchymal neoplasm with meningea...

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Bibliographic Details
Published in:International journal of surgical pathology 2023-06, Vol.31 (4), p.478-484
Main Authors: Pattnaik, Niharika, Parmar, Rajni, Nayak, Biswaranjan, Sampat, Nakul Y., Jha, Shilpy, Jena, Manas R., Barik, Lalit M., Mishra, Sourav K., Munjal, Gauri, Chottaraji, Anirudha, Mohanty, Sambit K.
Format: Article
Language:English
Subjects:
Case reports
Diagnosis, Differential
Histiocytosis, Sinus - diagnosis
Histiocytosis, Sinus - pathology
Histopathology
Humans
Male
Meninges - pathology
Middle Aged
Rare diseases
Tumors
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Summary:Meningeal Rosai-Dorfman disease, a type of sporadic Rosai-Dorfman disease, is a rare occurrence. A few cases are reported in the English literature with an adequate immunohistochemical workup. This entity clinically and radiologically mimics either a meningeal or a parenchymal neoplasm with meningeal extension, warranting a thorough histopathologic evaluation. A broad histologic differential necessitates a detailed immunohistochemical characterization to render a correct diagnosis that has significant therapeutic and prognostic implications. Herein, we report a case of isolated meningeal Rosai-Dorfman disease in a 50-years-old human immunodeficiency virus-positive male patient with an emphasis on the histopathology, immunoprofile, and differential diagnoses.
ISSN:1066-8969
1940-2465
DOI:10.1177/10668969221102615