“Age is just a number”; frailty as a marker of peri‐operative risk in head and neck surgery: Systematic review and meta‐analysis

Background Frailty refers to a patient's reduced capacity to withstand stressors due to a reduction in physiologic reserves. We assessed the impact of frailty on outcomes following head and neck surgery. Methods We performed a systematic review in accordance with the PRISMA guidelines. Meta‐ana...

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Bibliographic Details
Published in:Head & neck 2022-08, Vol.44 (8), p.1927-1939
Main Authors: Cleere, Eoin F., Davey, Matthew G., O'Neill, James P.
Format: Article
Language:English
Subjects:
elderly
Frailty
Head and neck
Meta-analysis
Morbidity
oncogeriatrics
Patients
Surgery
Systematic review
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Summary:Background Frailty refers to a patient's reduced capacity to withstand stressors due to a reduction in physiologic reserves. We assessed the impact of frailty on outcomes following head and neck surgery. Methods We performed a systematic review in accordance with the PRISMA guidelines. Meta‐analysis was performed using the Mantel–Haenszel method. Results Fourteen studies incorporating 182 059 patients were included in qualitative synthesis with 15 953 (8.8%) of patients deemed as frail. Meta‐analysis incorporating nine studies demonstrated that frailty is associated with an increased 30 day postoperative morbidity (OR 2.74; 95% CI 1.98–3.80; p 
ISSN:1043-3074
1097-0347
DOI:10.1002/hed.27110