Exercise reduces the risk of chronic kidney disease in individuals with nonalcoholic fatty liver disease: A nationwide cohort study

Recent studies of individuals with nonalcoholic fatty liver disease (NAFLD) have indicated benefits of exercise in improving outcomes. We investigated whether exercise reduces the risk of chronic kidney disease (CKD) in individuals with NAFLD. A total of 7275 participants from the Korea National Hea...

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Bibliographic Details
Published in:Diabetes & metabolism 2022-09, Vol.48 (5), p.101362-101362, Article 101362
Main Authors: Jung, Chan-Young, Chun, Ho Soo, Lee, Minjong, Koh, Hee Byung, Park, Keun Hyung, Joo, Young Su, Kim, Hyung Woo, Ahn, Sang Hoon, Park, Jung Tak, Kim, Seung Up
Format: Article
Language:English
Subjects:
Chronic kidney disease
Exercise
Lifestyle
Nonalcoholic fatty liver disease
Sedentary
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Summary:Recent studies of individuals with nonalcoholic fatty liver disease (NAFLD) have indicated benefits of exercise in improving outcomes. We investigated whether exercise reduces the risk of chronic kidney disease (CKD) in individuals with NAFLD. A total of 7275 participants from the Korea National Health and Nutrition Examination Survey (KNHANES) cohort, and 40,418 participants with NAFLD from the National Health Insurance Service (NHIS) cohort were included for the cross-sectional and longitudinal analyses, respectively. For the cross-sectional analysis, the primary outcome was prevalent CKD, defined as an estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73m2. For the longitudinal analysis, the primary outcome was incident CKD, defined as the occurrence of eGFR
ISSN:1262-3636
1878-1780
DOI:10.1016/j.diabet.2022.101362