Investigation of dynamic hyperinflation and its relationship with exercise capacity in children with bronchiectasis

Background and Aim Dynamic hyperinflation (DH) is a major contributor to exercise intolerance in patients with obstructive lung diseases. However, it has not been investigated in children with bronchiectasis (BE). We aimed to investigate dynamic ventilatory responses and their influence on functiona...

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Bibliographic Details
Published in:Pediatric pulmonology 2022-09, Vol.57 (9), p.2218-2226
Main Authors: Caglar Tosun, Beyza Nur, Zeren, Melih, Barlik, Meral, Demir, Esen, Gulen, Figen
Format: Article
Language:English
Subjects:
breathing reserve
bronchiectasis
Bronchitis
dynamic hyperinflation
Exercise
functional exercise capacity
lung function
Muscle strength
Respiration
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Summary:Background and Aim Dynamic hyperinflation (DH) is a major contributor to exercise intolerance in patients with obstructive lung diseases. However, it has not been investigated in children with bronchiectasis (BE). We aimed to investigate dynamic ventilatory responses and their influence on functional exercise capacity in children with BE. Methods Forty children with BE (mean forced expiratory volume in 1 s [FEV1] = 78 ± 19%pred) were included. Six‐minute walk test (6MWT) was conducted using Spiropalm 6MWT® for evaluating dynamic ventilatory responses including inspiratory capacity (IC), minute ventilation (VE), breathing reserve (BR) and respiratory rate (RR). A decrease of ≥100 ml in IC during exertion was defined as DH. Also, spirometry was performed, and peripheral muscle strength were measured. Results Twenty patients (50%) developed DH, and four patients (10%) were ventilatory limited (BR 
ISSN:8755-6863
1099-0496
DOI:10.1002/ppul.26028