Frailty Assessment for Outcome Prediction of Patients With Prostate Cancer Receiving Radical Prostatectomy: A Meta-Analysis of Cohort Studies

A meta-analysis was conducted to investigate the association between frailty and postoperative complications in patients with prostate cancer following radical prostatectomy. A systematic search of PubMed, Embase, and Web of Science was conducted for relevant cohort studies. A random-effect model wa...

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Bibliographic Details
Published in:Clinical nursing research 2022-07, Vol.31 (6), p.1136-1147
Main Authors: Liu, Xin, Sun, Weihang
Format: Article
Language:English
Subjects:
Cancer surgery
Clinical outcomes
Cohort analysis
Cohort Studies
Complications
Frailty
Frailty - complications
Frailty - surgery
Humans
Male
Meta-analysis
Mortality
Perioperative care
Postoperative Complications - etiology
Postoperative Complications - surgery
Postoperative morbidity
Prostate
Prostate cancer
Prostatectomy - adverse effects
Prostatectomy - methods
Prostatic Neoplasms - surgery
Robotic Surgical Procedures - adverse effects
Robotic Surgical Procedures - methods
Urological surgery
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Summary:A meta-analysis was conducted to investigate the association between frailty and postoperative complications in patients with prostate cancer following radical prostatectomy. A systematic search of PubMed, Embase, and Web of Science was conducted for relevant cohort studies. A random-effect model was chosen to combine the results. Five cohort studies including 171,929 patients were included. Results showed that patients with frailty had higher risk of severe postoperative complications (Clavien-Dindo IV complications, risk ratio [RR]: 1.87, 95% confidence interval [CI]: 1.67 to 2.10, p 
ISSN:1054-7738
1552-3799
DOI:10.1177/10547738221100350