Cell biology: How to short-circuit the cell cycle

Although the cell cycle normally progresses from G1toStoG2toM and then back to G1, certain manipulations have been found to ‘short circuit’ the cycle, causing repetitions of some stages while skipping others. A new study suggests how these changes limit the actions of molecular ‘latches’ that normal...

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Bibliographic Details
Published in:Current biology 2022-06, Vol.32 (12), p.R561-R563
Main Authors: Goldberg, Michael L., Gunaratne, Gemunu H.
Format: Article
Language:English
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Summary:Although the cell cycle normally progresses from G1toStoG2toM and then back to G1, certain manipulations have been found to ‘short circuit’ the cycle, causing repetitions of some stages while skipping others. A new study suggests how these changes limit the actions of molecular ‘latches’ that normally ensure orderly cell cycle progression. Although the cell cycle normally progresses from G1toStoG2toM and then back to G1, certain manipulations have been found to ‘short circuit’ the cycle, causing repetitions of some stages while skipping others. A new study suggests how these changes limit the actions of molecular ‘latches’ that normally ensure orderly cell cycle progression.
ISSN:0960-9822
1879-0445
DOI:10.1016/j.cub.2022.05.013