Nrf2 pathway in vegetable oil-induced inflammation of large yellow croaker (Larimichthys crocea)

This study was conducted to investigate the effects and regulation of dietary vegetable oil (VO, enriched with α-linolenic acid [ALA] and linoleic acid [LNA]) on the nuclear factor erythroid 2-related factor 2 (Nrf2) and nuclear factor-κB (NF-κB) pathways in large yellow croaker. In vivo study showe...

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Bibliographic Details
Published in:Fish & shellfish immunology 2022-08, Vol.127, p.778-787
Main Authors: Tan, Peng, Ding, Yi, Li, Xueshan, Dong, Xiaojing, Mai, Kangsen, Ai, Qinghui
Format: Article
Language:English
Subjects:
Fish oil
Larimichthys crocea
Nuclear factor erythroid 2-related factor 2
Nuclear factor-κB
Vegetable oil
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Summary:This study was conducted to investigate the effects and regulation of dietary vegetable oil (VO, enriched with α-linolenic acid [ALA] and linoleic acid [LNA]) on the nuclear factor erythroid 2-related factor 2 (Nrf2) and nuclear factor-κB (NF-κB) pathways in large yellow croaker. In vivo study showed that the VO diet significantly decreased the activity of antioxidant enzymes and antioxidant enzyme-related mRNA expression in the liver tissue, in comparison with the fish oil (FO) diet (P 
ISSN:1050-4648
1095-9947
DOI:10.1016/j.fsi.2022.05.046