Blood biomarkers as diagnostic tools: An overview of climate-driven stress responses in fish

• Published in: The Science of the total environment 2022-10, Vol.843, p.156910-156910, Article 156910
• Main Authors: Shahjahan, Md, Islam, Md Jakiul, Hossain, Md Tahmeed, Mishu, Moshiul Alam, Hasan, Jabed, Brown, Christopher
• Format: Article
• Language: English
• Subjects: acclimation; Antioxidants; Aquaculture; biomarkers; blood sampling; blood serum; climate change; environment; fish; functional status; hematologic tests; metabolites; Oxygen; Physiology; Salinity; storage time; Stress; Temperature; transportation; water quality
• ISSN: 0048-9697; 1879-1026
• DOI: 10.1016/j.scitotenv.2022.156910

Global climate change due to anthropogenic activities affects the dynamics of aquatic communities by altering the adaptive capacities of their inhabitants. Analysis of blood provides valuable insights in the form of a comprehensive representation of the physiological and functional status of fish under various environmental and treatment conditions. This review synthesizes currently available information about blood biomarkers used in climate change induced stress responses in fish. Alterations in informative blood-based indicators are used to monitor the physiological fitness of individual fishes or entire populations. Specific characteristics of fish blood, such as serum and plasma metabolites, cell composition, cellular abnormalities, cellular and antioxidant enzymes necessitate adapted protocols, as well as careful attention to experimental designs and meticulous interpretation of patterns of data. Moreover, the sampling technique, transportation, type of culture system, acclimation procedure, and water quality must all be considered for valid interpretation of hemato-biochemical parameters. Besides, blood collection, handling, and storage time of blood samples can all have significant impacts on the results of a hematological analysis, so it is optimal to perform hemato-biochemical evaluations immediately after blood collection because long-term storage can alter the results of the analyses, at least in part as a result of storage-related degenerative changes that may occur. However, the scarcity of high-throughput sophisticated approaches makes fish blood examination studies promising for climate-driven stress responses in fish. [Display omitted] •Global climate change due to anthropogenic activities affects the dynamics of aquatic communities.•Alterations in informative blood-based indicators are used to monitor the physiological fitness of an individual fish or an entire population.•Abnormal changes to temperature, light, salinity, oxygen, acidification, and inclusion of pesticides, heavy metals, microplastics etc. in the habitat are expected reasons for the deviation of hemato-biochemical parameters in fish.•The review summarizes the blood analyses those provide a comprehensive picture of physiological status of fish under various environmental and treatment conditions.