Liver and kidney toxicity caused by wild mushroom poisoning

Plasma exchange was performed along with treatments including 20% albumin, high-dose penicillin, N-acetylcysteine injection and Ganoderma lucidum. The patient's grandmother and aunt consumed the other half of the same mushroom (Fig a) and other mushrooms (Fig b and c), and both were admitted to...

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Bibliographic Details
Published in:Hong Kong medical journal = Xianggang yi xue za zhi 2022-06, Vol.28 (3), p.271-271.e2
Main Authors: Yang, L F, Zhu, L P, Li, Y T, Zhong, X B, Chen, Z G, Leung, Karen KY, Hon, K L
Format: Article
Language:English
Subjects:
Drug dosages
Liver
Medical prognosis
Mushrooms
Patients
Poisoning
Online Access:Get full text
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Summary:Plasma exchange was performed along with treatments including 20% albumin, high-dose penicillin, N-acetylcysteine injection and Ganoderma lucidum. The patient's grandmother and aunt consumed the other half of the same mushroom (Fig a) and other mushrooms (Fig b and c), and both were admitted to hospital with serious vomiting, diarrhoea and mild abdominal pain. Prognosis is often poor for patients with long incubation period of gastrointestinal symptoms ([greater than]6 hr), early manifestations of liver and kidney dysfunction, and multiple organ dysfunction.3 4Plasma exchange effectively removes hepatotoxins and improves survival, drugs such as silybin, N-acetylcysteine, putatively ceftazidime/penicillin and Ganoderma lucidum can also have a significant benefit.5 Ganoderma lucidum contains triterpenoids that can protect the liver and reduce oxidative stress and apoptosis.
ISSN:1024-2708
2226-8707
DOI:10.12809/hkmj208892