Disparities in the impact of the AJCC 8th edition staging system on differentiated thyroid cancer outcomes

Background The impact of AJCC8 among self‐reported racial/ethnic groups on differentiated thyroid cancer (DTC) outcomes is unknown. Methods Multivariate‐regression evaluated the association between AJCC7 to AJCC8 stage change and race/ethnicity in patients with DTC in the NCDB. Cox‐proportional‐regr...

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Bibliographic Details
Published in:Head & neck 2022-10, Vol.44 (10), p.2129-2141
Main Authors: Santamaria‐Barria, Juan A., Graff‐Baker, Amanda N., Chang, Shu‐Ching, Khader, Adam, Scholer, Anthony J., Garland‐Kledzik, Mary, Goldfarb, Melanie
Format: Article
Language:English
Subjects:
cancer staging
differentiated thyroid cancer
disparities
Ethnicity
Hispanic people
Minority & ethnic groups
Race
Survival
Thyroid cancer
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Summary:Background The impact of AJCC8 among self‐reported racial/ethnic groups on differentiated thyroid cancer (DTC) outcomes is unknown. Methods Multivariate‐regression evaluated the association between AJCC7 to AJCC8 stage change and race/ethnicity in patients with DTC in the NCDB. Cox‐proportional‐regression evaluated whether AJCC7 to AJCC8 stage change affects overall survival (OS) differently based on reported race/ethnicity. Results After adjusting for confounders, Hispanics and Asian‐Pacific‐Islanders (APIs) were 27% and 12% less likely to be down‐staged compared to white‐non‐Hispanics (WNHs) (p 
ISSN:1043-3074
1097-0347
DOI:10.1002/hed.27122