Perinatal and neonatal outcomes of women with very early preterm premature rupture of membranes treated via serial transabdominal amnioinfusion and expectant management: Experience of a tertiary referral center in Turkey

• Published in: The journal of obstetrics and gynaecology research 2022-07, Vol.48 (7), p.1732-1739
• Main Authors: Melekoglu, Rauf, Celik, Ebru
• Format: Article
• Language: English
• Subjects: amnioinfusion; amniotic fluid; Disease management; expectant management; Gestational age; Infant mortality; Latency; Morbidity; Mortality; Neonates; pregnancy outcomes; preterm premature rupture of fetal membranes; Rupture
• ISSN: 1341-8076; 1447-0756
• DOI: 10.1111/jog.15290

Aim We compared the outcomes of serial transabdominal amnioinfusion and expectant management on the perinatal and neonatal outcomes of pregnancies complicated with very early preterm premature rupture of membranes (PPROM). Methods We retrospectively reviewed the records of patients with very early PPROM admitted to the University of Inonu School of Medicine from 2014 to 2019. All such patients received comprehensive counseling on the possible prognoses; all were offered pregnancy termination, expectant management, and serial transabdominal infusion. Results Sixty‐three women met the inclusion criteria; 36 were assigned to the expectant management group and 27 were assigned to the amnioinfusion group. The median delivery latency and the gestational age at delivery were significantly higher in the amnioinfusion than the expectant management group [35 (11–90), 14 (7–48), p