Trehalose: a promising osmo-protectant against salinity stress—physiological and molecular mechanisms and future prospective

• Published in: Molecular biology reports 2022-12, Vol.49 (12), p.11255-11271
• Main Authors: Nawaz, Muhammad, Hassan, Muhammad Umair, Chattha, Muhammad Umer, Mahmood, Athar, Shah, Adnan Noor, Hashem, Mohamed, Alamri, Saad, Batool, Maria, Rasheed, Adnan, Thabit, Maryam A., Alhaithloul, Haifa A. S., Qari, Sameer H.
• Format: Article
• Language: English
• Subjects: Abiotic stress; Animal Anatomy; Animal Biochemistry; Antioxidants; Biomedical and Life Sciences; Cell membranes; Electrolyte leakage; Gas exchange; Histology; Life Sciences; Molecular modelling; Morphology; Nutrient uptake; Original Article; Osmoprotectants; Photosynthetic apparatus; Physiology; Plant tolerance; Progress in genomics; Salinity; Salinity effects; Salinity tolerance; transcriptomics and breeding of crops; Trehalose; Water relations; Water uptake
• ISSN: 0301-4851; 1573-4978
• DOI: 10.1007/s11033-022-07681-x

Salt stress is one of the leading threats to crop growth and productivity across the globe. Salt stress induces serious alterations in plant physiological, metabolic, biochemical functioning and it also disturbs antioxidant activities, cellular membranes, photosynthetic performance, nutrient uptake and plant water uptake and resulting in a significant reduction in growth and production. The application of osmoprotectants is considered as an important strategy to induce salt tolerance in plants. Trehalose (Tre) has emerged an excellent osmolyte to induce salinity tolerance and it got considerable attention in recent times. Under salinity stress, Tre helps to maintain the membrane integrity, and improves plant water relations, nutrient uptake and reduces the electrolyte leakage and lipid per-oxidation. Tre also improves gas exchange characteristics, protects the photosynthetic apparatus from salinity induced oxidative damages and brings ultra-structure changes in the plant body to induce salinity tolerance. Moreover, Tre also improves antioxidant activities and expression of stress responsive proteins and genes and confers salt tolerance in plants. Additionally, Tre is also involved in signaling association with signaling molecules and phytohormones and resultantly improved the plant performance under salt stress. Thus, it is interesting to understand the role of Tre in mediating the salinity tolerance in plants. Therefore, in this review we have summarized the different physiological and molecular roles of Tre to induce salt tolerance in plants. Moreover, we have also provided the information on Tre cross-talk with various osmolytes and hormones, and its role in stress responsive genes and antioxidant activities. Lastly, we also shed light on research gaps that need to be addressed in future studies. Therefore, this review will help the scientists to learn more about the Tre in changing climate conditions and it will also provide new insights to insights that could be used to develop salinity tolerance in plants.