Early histological changes of bronchopulmonary dysplasia and pulmonary hypertension may precede clinical diagnosis in preterm infants

AbstractBronchopulmonary Dysplasia (BPD), the commonest complication of prematurity, is defined by treatment with oxygen for ≥28 days. Pulmonary hypertension (PH) often coexists with BPD and is associated with increased mortality. In 42 autopsies, histological changes of BPD and PH were demonstrated...

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Published in:Early human development 2022-08, Vol.171, p.105612-105612, Article 105612
Main Authors: Stone, Amelia, Poulik, Janet, Koussa, Sara, Xin, Yuemin, Sharma, Amit, Sood, Beena G
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Language:English
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Advanced Basic Science
Neonatal and Perinatal Medicine
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description AbstractBronchopulmonary Dysplasia (BPD), the commonest complication of prematurity, is defined by treatment with oxygen for ≥28 days. Pulmonary hypertension (PH) often coexists with BPD and is associated with increased mortality. In 42 autopsies, histological changes of BPD and PH were demonstrated in 25 % and 65 % respectively of preterm infants
doi_str_mv 10.1016/j.earlhumdev.2022.105612
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Neonatal and Perinatal Medicine
title Early histological changes of bronchopulmonary dysplasia and pulmonary hypertension may precede clinical diagnosis in preterm infants
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