Effects of postnatal hydrocortisone on cytokine profile in extremely preterm infants

Background Systemic hydrocortisone administration has been widely used in preterm infants who are at risk of bronchopulmonary dysplasia (BPD). However, the effects of hydrocortisone on cytokine profiles have not been examined. We aimed to investigate the effects of postnatal hydrocortisone treatment...

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Bibliographic Details
Published in:Pediatrics international 2022-01, Vol.64 (1), p.e15205-n/a
Main Authors: Tamura, Kentaro, Nagaoka, Mitsuhide, Inomata, Satomi, Kawasaki, Yukako, Makimoto, Masami, Yoshida, Taketoshi
Format: Article
Language:English
Subjects:
bronchopulmonary dysplasia
Chemokines
cytokine
Cytokines
Gestational age
Helper cells
Hydrocortisone
Infants
Inflammation
Interleukin 6
Lymphocytes T
Neonates
Newborn babies
Pediatrics
Premature babies
preterm infant
Steroids
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Summary:Background Systemic hydrocortisone administration has been widely used in preterm infants who are at risk of bronchopulmonary dysplasia (BPD). However, the effects of hydrocortisone on cytokine profiles have not been examined. We aimed to investigate the effects of postnatal hydrocortisone treatment on serum cytokine levels in extremely preterm infants. Methods This is a retrospective study of 29 extremely preterm infants born at
ISSN:1328-8067
1442-200X
DOI:10.1111/ped.15205