High serum total cholesterol associated with good outcome in endovascular thrombectomy for acute large artery occlusion

Background The effect of cholesterol on the functional outcome after endovascular thrombectomy (EVT) is still controversial. This study aimed to investigate whether the lipid profile is associated with the EVT prognosis. Methods We retrospectively analyzed patients with emergent large vessel occlusi...

Full description

Saved in:
Bibliographic Details
Published in:Neurological sciences 2022-10, Vol.43 (10), p.5985-5991
Main Authors: Ha, Sang Hee, Ryu, Jae-Chan, Bae, Jae-Han, Koo, Sujin, Kwon, Boseong, Song, Yunsun, Lee, Deok Hee, Chang, Jun Young, Kang, Dong-Wha, Kwon, Sun U., Kim, Jong S., Kim, Bum Joon
Format: Article
Language:English
Subjects:
Arteriosclerosis
Cardiovascular system
Cholesterol
Diabetes mellitus
Hemorrhage
Lipids
Medicine
Medicine & Public Health
Neurology
Neuroradiology
Neurosciences
Neurosurgery
Occlusion
Original Article
Patients
Psychiatry
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background The effect of cholesterol on the functional outcome after endovascular thrombectomy (EVT) is still controversial. This study aimed to investigate whether the lipid profile is associated with the EVT prognosis. Methods We retrospectively analyzed patients with emergent large vessel occlusion who underwent EVT. The blood lipid levels were measured in the fasting state, 1 day after admission. We divided patients into terciles of serum total cholesterol (TC) levels and compared the clinical characteristics among the groups. The factors associated with a good outcome at 3 months (modified Rankin scale 0–2) were investigated, considering the stroke mechanism and recanalization status. Results Among 274 patients, good outcomes were observed in 108 (39.4%) patients. Low initial severity (odds ratio (OR), 0.91, 95% confidence interval (CI), 0.858–0.954; p  
ISSN:1590-1874
1590-3478
DOI:10.1007/s10072-022-06269-4