Role of arterial stiffness and endothelial dysfunction on lower limb performance in older adults with type 2 diabetes: A cross-sectional study

To verify whether arterial stiffness and endothelial dysfunction influence lower limb muscle strength and gait speed in older adults with type 2 diabetes mellitus (T2DM). Cross-sectional study including seventy-eight older adults with T2DM (aged 67 ± 6 years and 42 % male). Arterial stiffness was as...

Full description

Saved in:
Bibliographic Details
Published in:Journal of diabetes and its complications 2022-08, Vol.36 (8), p.108260-108260, Article 108260
Main Authors: Heubel, Alessandro Domingues, Kabbach, Erika Zavaglia, Migliato, Guilherme Romano, Russo, Maria Isabella Santos, Brandão, Gustavo Muçouçah Sampaio, Roscani, Meliza Goi, Borghi-Silva, Audrey, Mendes, Renata Gonçalves
Format: Article
Language:English
Subjects:
Age
Aging
Arterial stiffness
Bioavailability
Body mass index
Cross-sectional studies
Diabetes
Endothelial function
Gait
Gait speed
Muscle strength
Nitric oxide
Older people
Population
Regression analysis
Software
Type 2 diabetes
Walking
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To verify whether arterial stiffness and endothelial dysfunction influence lower limb muscle strength and gait speed in older adults with type 2 diabetes mellitus (T2DM). Cross-sectional study including seventy-eight older adults with T2DM (aged 67 ± 6 years and 42 % male). Arterial stiffness was assessed using pulse wave velocity (PWV), while endothelial function was measured by flow-mediated dilation (FMD). Lower limb muscle strength and gait speed were assessed using the 30-second chair stand test (30s-CST) and 10-Meter Walk Test, respectively. Both PWV (m/s) and FMD (%) were univariately associated with number of repetitions in 30s-CST and gait speed (P 
ISSN:1056-8727
1873-460X
DOI:10.1016/j.jdiacomp.2022.108260