Immune response in sexual inverted and non-inverted Nile tilapia fingerlings supplemented with organic acid and essential oil

The development and intensification of tilapia farming depends on the manipulation of some physiological functions, such as the sexual inversion of larvae using a synthetic androgen (17α-methyltestosterone). This inversion, however, may represent a potential oxidative stress factor and cause damage...

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Bibliographic Details
Published in:Fish & shellfish immunology 2022-08, Vol.127, p.975-981
Main Authors: Casetta, Jaísa, Gasparino, Eliane, Isabela da Silva, Caroline, Ribeiro, Ricardo Pereira, Braccini, Graciela Lucca, Refundini, Gislaine, de Souza Khatlab, Angélica, Lala, Bruno, Claudino-Silva, Stefania
Format: Article
Language:English
Subjects:
Enzymatic activity
Fish hematology
HSP70
Oreochromis niloticus
Protein oxidation
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Summary:The development and intensification of tilapia farming depends on the manipulation of some physiological functions, such as the sexual inversion of larvae using a synthetic androgen (17α-methyltestosterone). This inversion, however, may represent a potential oxidative stress factor and cause damage to animals in the short, medium, and long term. Dietary supplementation of natural antioxidant compounds is an interesting alternative to combat such damage. To test this hypothesis, an experimental trial was carried out involving sexual inverted and non-inverted Nile tilapia fingerlings, both supplemented and not supplemented with a blend of organic acids and essential oils protected by microencapsulation. Animals were divided into four experimental groups: NI (non-inverted animals), I (sexual inverted animals), NI + M (non-inverted animals supplemented with microcapsules), and I + M (sexual inverted animals supplemented with microcapsules). Blood parameters (WBC - white blood cells; LY - lymphocytes; RBC - red blood cells; HGB - hemoglobin; HCT – hematocrit number; MCH - mean corpuscular hemoglobin; MCV - mean corpuscular volume and MCHC – mean corpuscular hemoglobin concentration), as well as oxidative stress markers (enzymatic activity of superoxide dismutase – SOD and catalase - CAT; and total antioxidant capacity - 2,2-diphenyl-1-picryl-hydrazyl (DPPH)) and gene expression (heat shock protein 70 kDa - HSP70) were evaluated. The HGB (p 
ISSN:1050-4648
1095-9947
DOI:10.1016/j.fsi.2022.07.023