In vitro evaluation of pediatric restorative materials on human dental pulp stem cells

This in vitro study aimed to compare the cellular viability of four different restorative materials on human dental pulp stem cells (hDPSCs). The necessary tissues of isolated hDPSCs were obtained from 10 impacted third molars of healthy individuals 19–25 years old undergoing surgical extraction. Th...

Full description

Saved in:
Bibliographic Details
Published in:Tissue & cell 2022-08, Vol.77, p.101871-101871, Article 101871
Main Authors: Ilisulu, S. Ceren, Oztop, Nur Ecem, Akkoc, Tunc, Seymen, Figen
Format: Article
Language:English
Subjects:
Annexin V
Cell viability
Human dental pulp
Restorative material
Stem cell
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This in vitro study aimed to compare the cellular viability of four different restorative materials on human dental pulp stem cells (hDPSCs). The necessary tissues of isolated hDPSCs were obtained from 10 impacted third molars of healthy individuals 19–25 years old undergoing surgical extraction. The effects of GC Fuji IX GP, GC EQUIA Forte, APA Glass Carbomer, and APA Esthetic Fill eluates on hDPSCs’ viability on the first, third, and seventh days were examined by flow cytometry using an Annexin V binding assay. The cell viability ratios differed significantly between the restorative material groups (p  0.05). When the rates of late apoptotic cells were compared between the groups, no significant difference was observed, except for with the control group, which had the lowest rate of late apoptotic cells (p 
ISSN:0040-8166
1532-3072
DOI:10.1016/j.tice.2022.101871