Characterization of Fluorescein Angiography Features in Pediatric Patients with Uveitis

To characterize fluorescein angiography (FA) features in pediatric uveitis. A retrospective cross-sectional study of pediatric uveitis patients in Atlanta, GA, who had FA imaging between May 2009 and August 2020. A total of 137 eyes of 88 patients were evaluated. The mean FA score in anterior uveiti...

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Bibliographic Details
Published in:Ocular immunology and inflammation 2023-09, Vol.ahead-of-print (ahead-of-print), p.1-5
Main Authors: Hossain, Homaira Ayesha, Ye, Sarah, Ward, Laura, O'Keefe, Ghazala D.
Format: Article
Language:English
Subjects:
Fluorescein angiography
ocular inflammation
pediatric imaging
uveitis
vascular leakage
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Summary:To characterize fluorescein angiography (FA) features in pediatric uveitis. A retrospective cross-sectional study of pediatric uveitis patients in Atlanta, GA, who had FA imaging between May 2009 and August 2020. A total of 137 eyes of 88 patients were evaluated. The mean FA score in anterior uveitis was lower than that in other categories (p = .0093). The mean FA score in the clinically active group was higher than that in the clinically inactive group (p = .0057). The mean FA score in eyes 20/40 or better was lower than that in other categories (p = .0292). Worse visual acuity was associated with retinal vascular staining/leakage, retinal staining/pooling, and neovascularization elsewhere. Non-infectious uveitis more often demonstrated optic disc hyperfluorescence, retinal vascular staining/leakage, capillary leakage, and pinpoint leaks, while infectious uveitis more often demonstrated retinal staining/pooling. A standardized quantitative FA scoring system can be useful in the characterization of uveitis in pediatric patients.
ISSN:0927-3948
1744-5078
DOI:10.1080/09273948.2022.2091616