Role of N7-methylguanosine (m7G) in cancer

N7-methylguanosine (m7G) is a significant RNA modification occurring during epigenetic regulation. An increasing number of investigations have proved that the effect of m7G in suppressing cancer deserves more attention. Herein, we explore potential valuable targets based on present studies of m7G-re...

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Bibliographic Details
Published in:Trends in cell biology 2022-10, Vol.32 (10), p.819-824
Main Authors: Chen, Yongping, Lin, Huiran, Miao, Lei, He, Jing
Format: Article
Language:English
Subjects:
cancer
Epigenesis, Genetic
Guanosine - analogs & derivatives
Humans
METTL1
N7-methylguanosine
Neoplasms - genetics
target
WDR4
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Summary:N7-methylguanosine (m7G) is a significant RNA modification occurring during epigenetic regulation. An increasing number of investigations have proved that the effect of m7G in suppressing cancer deserves more attention. Herein, we explore potential valuable targets based on present studies of m7G-related cancer to improve disease therapy and prognoses.
ISSN:0962-8924
1879-3088
DOI:10.1016/j.tcb.2022.07.001