Pharmacotherapy and Mortality in Chronic Obstructive Pulmonary Disease

The global Initiative for Chronic Obstructive Lung Disease report notes that enhancing patient survival is a key aspirational objective for COPD, which continues to be a leading cause of death worldwide (I). Statistically substantial effects on all-cause mortality have been observed in two recent cl...

Full description

Saved in:
Bibliographic Details
Published in:American journal of respiratory and critical care medicine 2022-11, Vol.206 (10), p.1201-1207
Main Authors: Halpin, David M G, Martinez, Fernando J
Format: Article
Language:English
Subjects:
Cardiovascular disease
Chronic obstructive pulmonary disease
Clinical trials
Drug therapy
Humans
Lung diseases
Mortality
Pulmonary Disease, Chronic Obstructive - drug therapy
Severity of Illness Index
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The global Initiative for Chronic Obstructive Lung Disease report notes that enhancing patient survival is a key aspirational objective for COPD, which continues to be a leading cause of death worldwide (I). Statistically substantial effects on all-cause mortality have been observed in two recent clinical trials, although the reliability of these results and their therapeutic applicability are still debatable. Better data are not expected to become available, so we must base our decision on the evidence that is already available. When seen holistically, the findings demonstrate that medication reduces mortality among patients with more serious disease who are at risk of exacerbations.
ISSN:1073-449X
1535-4970
DOI:10.1164/rccm.202205-1000PP