Indolent NK-Cell Lymphoproliferative Disorder of the Gastrointestinal Tract — a Report of two Cases of a new Provisional Entity on the World Health Organization Classification of Hematolymphoid Tumors

Indolent NK-cell lymphoproliferative disorder of the gastrointestinal tract is a new provisional entity listed in the structure of the forthcoming fifth edition of the World Health Organization (WHO) Classification of Hematolymphoid Tumors. It was first named as “NK-cell enteropathy” and “Lymphomato...

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Bibliographic Details
Published in:International journal of surgical pathology 2023-08, Vol.31 (5), p.596-599
Main Authors: Alves de Castro, João Víctor, Costa, Felipe D’Almeida, Ferreira, Cristiane Rúbia
Format: Article
Language:English
Subjects:
Cytogenetics
Digestive system
Lymphatic diseases
Lymphatic system
Tumors
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Summary:Indolent NK-cell lymphoproliferative disorder of the gastrointestinal tract is a new provisional entity listed in the structure of the forthcoming fifth edition of the World Health Organization (WHO) Classification of Hematolymphoid Tumors. It was first named as “NK-cell enteropathy” and “Lymphomatoid gastropathy” by two independent series a decade ago. Molecular or cytogenetic studies have lent support to the clonal/neoplastic nature of this entity. Herein we add two of such cases that still challenge pathologists and were previously diagnosed as aggressive lymphomas of NK/T derivation.
ISSN:1066-8969
1940-2465
DOI:10.1177/10668969221113474