Modelling the frontal lobes in health and disease

A simplified model of the architecture of the frontal lobes, the ACTION network, is applied to study the task of temporal sequence storage and generation. In particular we analyse the manner in which a hard-wired model of such storage is affected by damage corresponding to loss of dopamine. We find...

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Bibliographic Details
Main Authors: Taylor, N.R, Taylor, J.G
Format: Conference Proceeding
Language:English
Subjects:
Biology and medical computing
Brain models
Electrical activity in neurophysiological processes
General, theoretical, and mathematical biophysics
Neural computing techniques
Neural nets
Neurology
Systems theory applications in biology and medicine
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Summary:A simplified model of the architecture of the frontal lobes, the ACTION network, is applied to study the task of temporal sequence storage and generation. In particular we analyse the manner in which a hard-wired model of such storage is affected by damage corresponding to loss of dopamine. We find support for the DeLong model of 1990, in which the subthalamic nucleus in the indirect path plays an important role.
ISSN:0537-9989
DOI:10.1049/cp:19991142