Comparison of antiplaque and anti‐gingivitis effects of aloe vera mouthwash with chlorhexidine in fixed orthodontic patients—A randomized controlled trial

• Published in: International journal of dental hygiene 2023-02, Vol.21 (1), p.211-218
• Main Authors: Kamath, Deepa G., Nadimpalli, Harshitha, Nayak, Sangeeta Umesh, Rajendran, Valliammai, Natarajan, Srikant
• Format: Article
• Language: English
• Subjects: Aloe; aloe vera; Biofilms; Bleeding; Chlorhexidine; Chlorhexidine - therapeutic use; Clinical trials; Dental plaque; Dental Plaque - drug therapy; Dental Plaque - prevention & control; Dentistry; fixed orthodontic treatment; Gingival index; Gingivitis; Gingivitis - drug therapy; Gingivitis - prevention & control; Humans; Hygiene; mouth rinse; Mouthwashes; Mouthwashes - therapeutic use; Oral diseases; Oral hygiene; Orthodontics; Patients; Periodontal diseases; Plaque index; Statistical analysis
• ISSN: 1601-5029; 1601-5037
• DOI: 10.1111/idh.12615

Background In daily dental practice, plaque‐induced gingivitis is one of the most common periodontal diseases that is frequently encountered. Accumulation of microbial biofilms on surfaces of teeth and poor or inadequate oral hygiene is the chief predisposing factor for this condition. In such a state, antimicrobial mouthwash as an adjunct to mechanical plaque control helps in maintaining good oral hygiene. Among the many conditions, fixed orthodontic treatment is one of the conditions where plaque control becomes challenging to the patient as well as the dentist. In such a situation, antimicrobial mouthwash as an adjunct to mechanical plaque control is highly recommended. Dentistry has recently evidenced a shift of approach for treating many inflammatory oral diseases by using herbal treatment modalities. Aloe vera is one such product exhibiting multiple benefits and has gained considerable importance in clinical research recently. The present study aimed to evaluate efficacy of aloe vera mouth rinse on the dental plaque and gingivitis in patients who were undergoing fixed orthodontic treatment in comparison with 0.2% chlorhexidine mouthwash. Material and Method This randomized controlled trial was conducted on 30 subjects with fixed orthodontic treatment. The subjects were grouped in the test group (15 subjects with 10 ml aloe vera mouthwash (99.6% [w/v])) and the control group (15 subjects with 0.2% 10 ml chlorhexidine mouthwash). Plaque index, gingival index and bleeding on probing were recorded for each participant at baseline, 21 days from baseline and 35 days from baseline. The findings were then statistically analysed using student paired and unpaired t‐test. Results Gingival index showed a statistically significant difference from baseline to 21 days and 35 days visit in both the groups. Plaque index and bleeding on probing were statistically significant among both groups when compared baseline to 21 days and 35 days visit, but the difference was not significant between visit 2 and visit 3. Conclusions Although chlorhexidine is still the gold standard mouthwash, aloe vera exhibits promising results in reducing plaque and gingivitis scores, without any reported adverse effects. Larger multi‐centric trials are needed to prove its effectiveness on dental plaque‐induced gingivitis.