Prevalence and associated factors for pterygium in a Chinese rural population with type 2 diabetes in a cross-sectional study: Jiangsu Diabetic Eye Disease Study (JDEDS)

• Published in: International ophthalmology 2023-02, Vol.43 (2), p.411-422
• Main Authors: Zhang, Junfang, Qin, Bai, Liu, Bihong, Sun, Dajun, Liang, Congkai, Wang, Shiyi, Yang, Mei, Zhu, Rongrong
• Format: Article
• Language: English
• Subjects: Aged; Aged, 80 and over; China - epidemiology; Cigarette smoking; Confidence intervals; Cross-Sectional Studies; Diabetes; Diabetes Complications - complications; Diabetes mellitus; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - epidemiology; East Asian People; Evaluation; Eye; Eye diseases; Female; Humans; Hypertension; Male; Medicine; Medicine & Public Health; Men; Middle Aged; Multivariate analysis; Ophthalmology; Original Paper; Pathogenesis; Prevalence; Pterygium - diagnosis; Pterygium - epidemiology; Pterygium - etiology; Regression analysis; Regression models; Risk Factors; Rural Population; Rural populations; Smoking; Statistical analysis; Women
• ISSN: 1573-2630; 0165-5701; 1573-2630
• DOI: 10.1007/s10792-022-02438-8

Purpose To investigate the pterygium prevalence and evaluate risk factors of pterygium in rural type 2 diabetic (D2M) patients aged 50 years and above in Funing Country, Jiangsu Province, China. Methods A cross-sectional ophthalmic survey was conducted in type 2 diabetes mellitus (D2M) patients aged ≥ 50 years in Funing County, Jiangsu Province, China, which was named Jiangsu Diabetic Eye Disease Study (JDEDS). All participants underwent a comprehensive questionnaire and ocular examination. Pterygium was diagnosed by slit lamp examination. The risk factors associated with pterygium were evaluated with logistic regression models. Results The prevalence of pterygium was 22.37% ( n  = 427) and 95% confidence interval (CI) (20.50–24.24%) in D2M patients aged 50 years and above in JDEDS. The prevalence of pterygium was 18.32% (95% CI 15.33–21.32%) in men and 24.43% (95% CI 22.06–26.80%) in women. Women had a higher prevalence than men ( p  = 0.001). Multivariate analysis showed, for male participants with D2M, pterygium was independently associated with increasing age [70–79 years: OR and 95% CI 2.49(1.20–5.18), p  = 0.014; ≥ 80 years: 4.84(2.04–11.47), p