Endoscopic Ultrasound-Directed Transgastric ERCP (EDGE) Utilization of Trends Among Interventional Endoscopists

• Published in: Digestive diseases and sciences 2023-04, Vol.68 (4), p.1167-1177
• Main Authors: Shah-Khan, Sardar M., Zhao, Eric, Tyberg, Amy, Sarkar, Sardar, Shahid, Haroon M., Duarte-Chavez, Rodrigo, Gaidhane, Monica, Kahaleh, Michel
• Format: Article
• Language: English
• Subjects: Biochemistry; Cholangiopancreatography, Endoscopic Retrograde - adverse effects; Cholangiopancreatography, Endoscopic Retrograde - methods; Endoscopy; Endoscopy, Gastrointestinal; Endosonography - methods; Gastric Bypass - adverse effects; Gastric Bypass - methods; Gastroenterology; Gastrointestinal surgery; Hepatology; Humans; Medicine; Medicine & Public Health; NCT; NCT05041608; Oncology; Original Article; Retrospective Studies; Transplant Surgery; Ultrasonic imaging; Weight Gain
• ISSN: 0163-2116; 1573-2568
• DOI: 10.1007/s10620-022-07650-1

Background Endoscopic ultrasound-directed transgastric ERCP (EDGE) has become standard-of-care therapy at many centers for pancreaticobiliary disease in patients with Roux-en-Y Gastric Bypass. In this study, we aimed to evaluate the opinions and practices of endoscopists who perform EDGE. Methods A 22-question utilization of EDGE survey was sent to 36 advanced endoscopists at tertiary care centers in the United States. The two-section survey included questions regarding advanced endoscopy volume and training at the respective facilities, and questions on specific details of EDGE utilization. Results Among 36 interventional endoscopists (IE) surveyed, 14 (39%) reported performing > 1000 ERCPs annually. Thirty (83%) offered EDGE as an option for Roux-en-Y gastric bypass patients with previous cholecystectomy. Other options offered included: 19 (53%) offered Laparoscopy-assisted ERCP (LA-ERCP), 7 (19%) offered Single-Balloon ERCP (SBE), and 10 (28%) offered percutaneous drainage (PTC). Twenty (56%) IE performed 10 or less EDGE procedures, while 16 (44%) performed 11 or more. Single-session EDGE was performed by 7 (19%) IE, while 15 (42%) performed dual session, and 13 (36%) performed both. 19 (53%) actively closed fistulas while 17 (47%) let them close spontaneously. Thirty one (86%) reported a technical success rate of 91% to 100%. The most frequently reported immediate adverse event post-procedurally was abdominal pain, reported by 17 IE (47%). Weight gain was reported by 2 IE (6%). Conclusion EDGE continues to gain in popularity as an option for Roux-en-Y gastric bypass patients requiring pancreaticobiliary interventions, with 24/36 IE (67%) believing that it should be the new standard. In addition, most report a low frequency of post-procedural weight gain. Clinical Trial Registration ClinicalTrials.gov Identifier NCT05041608.